Contact allergy (CA) is alteration of immune response with readiness to develop an inflammatory reaction against a specific substance of low molecular weight (hapten). The prevalence of CA is estimated at 26-40% among adults, and 21-36% children. A proportion of people with CA will remain asymptomatic, among the rest, the most frequent clinical manifestation is allergic contact dermatitis (ACD)...

Increasing fuel prices force the manufacturers to look into all aspects of car aerodynamics including wheels, tyres and rims in order to minimize their drag. By diminishing the aerodynamic drag of vehicle the fuel consumption will decrease, while driving safety and comfort will improve. In order to properly illustrate the impact of a rotating wheel aerodynamics on the car body, precise analysis...

BACKGROUND The prevalence of contact allergy to fragrance mix (FM) I varies from study to study, depending on factors such as test population, patch test material, and technique. OBJECTIVES To compare the outcome of routine patch testing with FM I TRUE Test and FM I Trolab. MATERIALS AND METHODS A total of 5006 consecutive eczema patients were patch tested with both patch test materials acc...

The term compound allergy is used to describe a condition in patients who are patch test-positive to formulated products, but are patch test-negative to all the ingredients when these are tested individually. We report 8 cases of contact dermatitis to VEA® lipogel (Ulka, Rovigo, Italy), a cosmetic that has previously been reported as the cause of compound allergy (1). All cases were observed at...

BACKGROUND The panel of patch test allergens used for the evaluation of patients with suspected photoallergy typically does not include plant and pesticide allergens. The prevalence of allergic contact dermatitis and photoallergic contact dermatitis to plant and pesticide allergens was determined for this subgroup of patients. OBSERVATION Positive reactions were detected in 12 of 26 patients ...

BACKGROUND Methyl 2-octynoate is a synthetic fragrance which was first described to have sensitizing properties in 1935. It is one of the 26 fragrances to be labelled on the ingredient list according to current European cosmetics regulation. OBJECTIVES To report the experience with patch testing with methyl 2-octynoate 1% and 2% in pet. METHODS 230 eczema patients were consecutively patch t...

We discuss cross-reactions that can occur when a patient allergic to a specific allergen also reacts to a similar allergen. Currently, The American Contact Dermatitis Society Contact Allergy Management Program, which allows physicians to identify safe products for their patients, uses a 10% threshold to distinguish significant cross-reactors. New clinical data from a patch testing center along ...