BACKGROUND Field studies of illicit anabolic-androgenic steroid users suggest that some develop manic or aggressive reactions to these drugs-a potential public health problem. However, controlled laboratory evaluations of these effects remain limited. METHODS In a randomized, placebo-controlled, crossover trial, we administered testosterone cypionate for 6 weeks in doses rising to 600 mg/wk a...

There is evidence in the IT literature indicating that IT management is one factor that influences IT success. In addition, there is much literature indicating that IT management is important in the SME context. However, much of this literature has focused on the important role of the owner and/or other senior managers. For example, Thong et al (1996) focused on top management support and its i...

We review key sessions on pharmacological treatment, including four on irritable bowel syndrome and others on pancreatitis and Helicobacter pylori infection.

4–7 July 2017, Poznań About Consisting of two workshops, Poznań Reasoning Week 2017 (PRW2017) brings together experts from various disciplines whose research offers both systematic and historical contributions to the study of individualas well as group-reasoning processes. This particularly includes, but is not restricted to, modelling these processes formally. Recent years have witnessed a cog...

I love PA Week. There is such a sense of excitement and pride as the profession acknowledges the past, celebrates the present, and looks to our future. My fi rst week in physician assistant (PA) education culminated in a Duke University PA Day celebration. I still remember these festivities 13 years later because it was the fi rst time I really thought about the history of the profession and th...

Etale cohomology. Lecture 15 (Oct. 27, 2008)

A linear program (LP for short) is an optimization problem in which the constraints are linear inequalities and equalities, and the objective function is also linear. There are many equivalent standard forms for LPs. We will use the following form for a maximization problem: max cx s.t. Ax ≤ b x ≥ 0 Let us explain the notation a bit. Here A is an m× n matrix (i.e. m constraints and n variables)...

antiviral agents, many patients face barriers to access. In our Advances in Hepatology column, Dr David E. Bernstein discusses factors that are restricting the use of these lifesaving therapies. A feature article by Drs Nicolas A. Villa and M. Edwyn Harrison describes the diagnosis, classification, and management of biliary strictures, a common complication of liver transplantation. Although bi...

ated Trade Unions, has recently ascended to the Throne on the death of Lord Williams, our beloved Monarch for so many years. His Lordship described the continuing success of the present form of government, which has so effectively resolved all the vexed Problems of party politics. He finished his distinguished oration by welcoming Lord Higgins, recently appointed to the peerage for his outstand...