Heparin was isolated from whole clam tissue Marcia opima . Purification of multimilligram quantities of heparin from this tissue sample permitted a thorough examination of its anticoagulant activity characterization, which was partially purified by fractionation by anion exchange chromatography using DEAE cellulose column. The isolated crude and partially purified fractionated sample showed me...

The cell-cycle checkpoint protein p53 both directs terminal differentiation and protects embryos from DNA damage. To study invertebrate p53 during early development, we identified three differentially expressed p53 family members (p53, p97, p120) in the surf clam, Spisula solidissima. In these mollusks, p53 and p97 occur in both embryonic and adult tissue, whereas p120 is exclusively embryonic....

The aim of this study was to evaluate the use of metal concentrations in clam organs to monitor metal contamination in coastal sediments. The concentrations of Cd, Cr, Cu, Hg, Ni, Pb, V, and Zn were measured in the kidneys, gonads, mantles, gills, digestive gland, and hearts of the infaunal clam Amiantis umbonella collected from a contaminated site near desalination and power plant discharges, ...

Cytoplasmic polyadenylation-element-binding protein (CPEB) is a well-characterized and important regulator of translation of maternal mRNA in early development in organisms ranging from worms, flies and clams to frogs and mice. Previous studies provided evidence that clam and Xenopus CPEB are hyperphosphorylated at germinal vesicle breakdown (GVBD) by cdc2 kinase, and degraded shortly after. To...

Quahog Parasite Unknown (QPX) is a fatal protistan parasite that causes severe losses in the hard clam (Mercenaria mercenaria) fisheries along the northeastern coast of the US. Field and laboratory studies of QPX disease have demonstrated a major role for water temperature and M. mercenaria genetic origin in disease development. Infections are more likely to occur at cold temperatures, with cla...

In this research, numerical simulation of a symmetric impact of a 2-D wedge, considering dynamic equations in two-phase flow is taken into account. The two-phase flow around the wedge is solved based on finite volume method and volume of fluid (VOF) scheme. The dynamic mesh model is used to simulate dynamic motion of the wedge, thereby the effects of different dynamic meshes in both structured ...

Figure 1. Giant clams: benign giants. (A) End view of a huge Tridacna gigas showing its expanded mantle (m) projecting over the sides of its shells (photo: Rick Braley). (B) A stained cross-section near the surface of a clam’s mantle tissue showing very densely packed symbiotic zooxanthellae and zooxanthellae aligned in ‘fingers’ (f). The zooxanthellae are ca. 8 μm in diameter. (C) An explosive...

Citation: Koh CZY, Hiong KC, Choo CYL, Boo MV, Wong WP, Chew SF, Neo ML and Ip YK (2018) Molecular Characterization of a Dual Domain Carbonic Anhydrase From the Ctenidium of the Giant Clam, Tridacna squamosa, and Its Expression Levels After Light Exposure, Cellular Localization, and Possible Role in the Uptake of Exogenous Inorganic Carbon. Front. Physiol. 9:281. doi: 10.3389/fphys.2018.00281 M...

BACKGROUND Wedge filters are commonly used in radiation oncology for eliminating hot spots and creating a uniform dose distribution in optimizing isodose curves in the target volume for clinical aspects. These are some limited standard physical wedges (15°, 30°, 45°, 60°),or creating an arbitrary wedge angle, like motorized wedge or dynamic wedge,... The new formulation is presented by the comb...