BACKGROUND DC shock catheter ablation for the treatment of ventricular tachycardia (VT) may induce VT episodes that disappear within days. METHODS AND RESULTS A 30-J cathodal shock was delivered to the endocardial left ventricular wall in 15 closed-chest dogs. All dogs had VT during the first day after ablation. Eleven of these dogs were studied on the first day. Extensive epicardial and endo...

PURPOSE The incorporation of doxorubicin in long-circulating sterically stabilized liposomes (SSL-DXR) alters the pharmacokinetics and biodistribution of doxorubicin and therefore has the potential to alter the pharmacologic properties of doxorubicin. Previously, we showed that repetitive administration of SSL-DXR alters tumor vascular permeability. EXPERIMENTAL DESIGN Here, we investigated t...

The existence conditions and waveguiding properties of new hybrid, TE-dominant waveguide modes of properly tailored waveguides consisting on ultrathin films cladded by a positive birefringent crystal are analyzed. The results show that the existence conditions of such waves strongly depend on the waveguide parameters. Accordingly, the related guided-toradiated wave transition holds promise for ...

As a major family of semi-supervised learning (SSL), graph-based SSL has recently attracted considerable interest in the machine learning community along with application areas such as video semantic analysis. In this paper, we analyze the connections between graph-based SSL and partial differential equation(PDE) based diffusion. From the viewpoint of PDE-based diffusion, the label propagation ...

In the present study, we prepared NGR-modified sterically stabilized liposomes containing paclitaxel (NGR-SSL-PTX) in order to evaluate their potential targeting to aminopeptidase N receptors expressed on tumor endothelial cells and the tumor cell surface and its anti-angiogenic activity following metronomic administration. NGR-SSL-PTX was prepared by a thin-film hydration method. The in vitro ...

We report electroabsorption modulation of light at around 1550 nm in a unipolar InGaAlAs optical waveguide containing an InGaAs/AlAs double-barrier resonant tunneling diode ~RTD!. The RTD peak-to-valley transition increases the electric field across the waveguide, which shifts the core material absorption band edge to longer wavelengths via the Franz–Keldysh effect, thus changing the light-guid...

Average users lack the technical expertise to understand SSL certificates and security is not their primary goal. Thus, it is very hard to create a notable impact on user behavior using SSL-status indicators. However, with the introduction of web browser Personas (simple skins) as a possibility to change the browser's chrome, it becomes possible to provide a large status indicator without wasti...

We study classical ${J}_{1}\ensuremath{-}{J}_{2}$ models with distinct spin degrees of freedom on a honeycomb lattice. For the XY and Heisenberg spins, system develops spiral liquid (SSL) that is thermal cooperative paramagnetic regime spins fluctuating around contours in momentum space, at low temperatures supports vector spin-chirality order despite absence long-range magnetic order. In stron...