introduction: recently, magnetic resonance spectroscopic imaging (mrsi), as a functional imaging method, has been used for clinical target volume definition. in this study, we used this method to define the target volume in prostate radiotherapy. material and method: in this study, we used images of 20 prostate cancer cases. mrsi and mri images were fused with ct images. then, treatment plannin...

Kinase inhibitors are important cancer drugs, but they tend to display limited target specificity, and their target profiles are often challenging to rationalize in terms of molecular mechanism. Here we report that the clinical kinase inhibitor bosutinib recognizes its kinase targets by engaging a pair of conserved structured water molecules in the active site and that many other kinase inhibit...

introduction: in the present study, dealing with water deficit challenges for gorgan river basin has been considered. golestan province's economy is dependent on agriculture but the occurrence of drought periods reduced the agricultural production and consequently the region's economy is in crisis. therefore, performing studies for programming and management of the water resources of the provin...

the allelopathic potential of the foliage tissues of eight barley cultivars was investigated using seedlings bioassays of indian brown mustard (brassica juncea) and green foxtail (setaria viridis) as typical broadleaf and grass weeds of the croplands. the correlations of allelochemical compounds with seed germination of weeds were determined. the barley cultivars used were jackson, bronco, cdc ...

Background: This retrospective study aimed to investigate the physicochemical properties of drinking water sources in Ethiopia and compare the water quality with the health-based target. For this purpose, the water quality database of Ethiopian Public Health Institute (EPHI) from 2010 to 2016 was used. Methods: The concentration and other properties of the water samples were analyzed according...

Postoperative radiotherapy is a major treatment for patients with maxillary sinus carcinoma. However, the irregular resection cavity poses a technical difficulty for this treatment, causing uneven dose distribution to target volumes. In this study, we evaluated the dose distribution to target volumes and normal tissues in postoperative intensity-modulated radiotherapy (IMRT) after placing a wat...

BACKGROUND Antibiotic residues are being constantly identified in environmental waters at low concentration. Growing concern has been expressed over the adverse environmental and human health effects even at low concentration. Hence, it is crucial to develop a multi-residues analytical method for antibiotics to generate a considerable dataset which are necessary in the assessment of aquatic tox...

Water resource management often requires an integrated assessment of resource use options, including local and regional impacts on the environment and stakeholders. The Upper South East of South Australia is one such location, where a large drainage network has been constructed to manage flooding, dryland salinity and environmental outcomes. Within the drainage network, there are a number of re...