OBJECTIVES We sought to examine whether patients with stable coronary artery disease (CAD) have increased platelet reactivity and an enhanced propensity to form monocyte-platelet aggregates. BACKGROUND Platelet-dependent thrombosis and leukocyte infiltration into the vessel wall are characteristic cellular events seen in atherosclerosis. METHODS Anticoagulated peripheral venous blood from 1...

Higher-order structures that originate from the specific and reversible DNA-directed self-assembly of microscopic building blocks hold great promise for future technologies. Here, we functionalized biotinylated soft colloid oil-in-water emulsion droplets with biotinylated single-stranded DNA oligonucleotides using streptavidin as an intermediary linker. We show the components of this modular li...

Naphthenic Acids (NA) are important oil extraction subproducts. These chemical species one of the leading causes marine pollution and duct corrosion. For this reason, understanding behavior NAs in different saline conditions is challenges industry. In work, we simulated several naphthenic acid their mixtures, employing density functional theory calculations with MST-IEFPCM continuum solvation m...

[1] We performed triaxial compressive creep tests to study water weakening of clinopyroxenite in the diffusion creep regime. All tests were carried out on fine-grained samples at confining pressures between 100 and 300 MPa at temperatures of 1321 to 1421 K for water-saturated and 1398 to 1508 K for anhydrous conditions. Samples were prepared by hot-pressing ground powder of Sleaford Bay clinopy...

BACKGROUND A novel chaperone, cpSRP43, recognizes and disassembles the aggregates formed by its client proteins. RESULTS The client proteins of cpSRP43 form stable disc-shaped aggregates with the chaperone recognition motif displayed onthe surface. CONCLUSION The surface-exposed motif on the aggregate allows it to be recognized by its chaperone. SIGNIFICANCE Understanding the structure an...

The hydrodynamic behavior of diatom aggregates has a significant influence on the interactions and flocculation kinetics of algae. However, characterization of the hydrodynamics of diatoms and diatom aggregates in water is rather difficult. In this laboratory study, an advanced visualization technique in particle image velocimetry (PIV) was employed to investigate the hydrodynamic properties of...

Background: A novel chaperone, cpSRP43, recognizes and disassembles the aggregates formed by its client proteins. Results: The client proteins of cpSRP43 form stable disc-shaped aggregates with the chaperone recognition motif displayed on the surface. Conclusion: The surface-exposed motif on the aggregate allows it to be recognized by its chaperone. Significance: Understanding the structure and...

We introduce a family of partial stable model semantics for logic programs with arbitrary aggregate relations. The semantics are parametrized by the interpretation of aggregate relations in three-valued logic. Any semantics in this family satisfies two important properties: (i) it extends the partial stable semantics for normal logic programs and (ii) total stable models are always minimal. We ...