Cognition is regulated across the 24 h sleep-wake cycle by circadian rhythmicity and sleep homeostasis through unknown brain mechanisms. We investigated these mechanisms in a functional magnetic resonance imaging study of executive function using a working memory 3-back task during a normal sleep-wake cycle and during sleep loss. The study population was stratified according to homozygosity for...

In this paper, based on flume experimental data, the velocity distribution in open channel flows is re-investigated. From the analysis, it is proposed that the wake layer in outer region may be divided into two regions, the relatively weak outer region and the relatively strong outer region. Combining the log law for inner region and the parabolic law for relatively strong outer region, an expl...

[1] The wake region of Titan is an important component of Titan’s interaction with its surrounding plasma and therefore a thorough understanding of its formation and structure is of primary interest. The Cassini spacecraft passed through the distant downstream region of Titan on 18:59:30 UT Dec. 26, 2005, which is referred to as the T9 flyby and provided a great opportunity to test our understa...

introduction: for a velocity profile in turbulent flows, the flow conditions in the vicinity of the wall are described by logarithmic law of the wall. however, it has been extensively verified that the log-law does not apply in the outer region of the boundary layer. for example, in free surface flows, the law of the wall holds only for 20 percent of the flow depth from the wall. coles (1956) c...

We propose a novel method for mitigating erroneous wake-ups that are commonly associated with ultra-low power wake-up receivers. Recent research in low-power protocols has demonstrated significant improvements in energy-efficiency by employing ultralow power wake-up receivers. However, due to the low-complexity receiver structures adopted, wake-up receivers are susceptible to external interfere...

The perifornical (PF) region of the posterior hypothalamus plays an important role in the regulation of sleep-wake states and motor activity. Disinhibition of PF neurons by the GABA(A) receptor antagonist, bicuculline, has been used to study the mechanisms of wake- and motor activity-promoting effects that emanate from the PF region. Bicuculline activates PF neurons, including the orexin-contai...

is a typical story. a patient arrives at the emergency room. he was well when he went to bed and then he woke up with symptoms suggestive of stroke several hours later. even without further scrutiny, the clinician determines that intravenous thrombolytic therapy is contraindicated. end of story. Such is the plight of patients with wake-up stroke. Can we do more? Can we do better? Wake-up stroke...