1 (Oral/Poster) MULTICELLULAR HUMAN TESTICULAR ORGANOID: A NOVEL IN VITRO GERM CELL AND TESTICULAR TOXICITY MODEL Samuel Pendergraft, MS1, Hooman Sadri-Ardekani, MD, PhD2, Tanya Reid, BS3, Anthony Atala, MD2 and Colin Bishop, PhD1 1(1) Molecular Medicine and Translational Science Graduate Program, Wake Forest University Health Sciences, Winston-Salem, NC (2) Wake Forest Institute for Regenerati...

OBJECTIVE Despite their high prevalence in daily life, repeated night-wakings and their cognitive and emotional consequences have received less research attention compared to other types of sleep disturbances. Our aim was to experimentally compare the effects of one night of induced infrequent night-wakings (of ∼15 min, each requiring a purposeful response) and sleep restriction on sustained at...

BACKGROUND Epileptic seizures, predominantly or exclusively during sleep had been the focus of attention for many electroencephalographers. Though few epileptic syndromes are associated with sleep seizures (SS) its frequencies in Indian patients is still unknown. AIM To find out the patterns of epilepsies in patients having SS and compare them with patients having wake seizures (WS). SETTIN...

The secondary instabilities in the wake of a circular cylinder with near-wake wire disturbances are investigated by using threedimensional (3D) direct numerical simulations (DNS). For one wire placed asymmetrical about the wake centreline and two wires placed symmetrical about the wake centreline, the secondary instabilities are found to be Mode C and Mode A, respectively. The existence of the ...

The transfer of momentum from an animal to fluid in its wake is fundamental to many swimming and flying modes of locomotion. Hence, properties of the wake are commonly studied in experiments to infer the magnitude and direction of locomotive forces. The determination of which wake properties are necessary and sufficient to empirically deduce swimming and flying forces is currently made ad hoc. ...

Schizophrenic patients suffer from more metabolic or sleep problems. Little is known about risk factors. We recruited 17 patients with chronic schizophrenia from the rehabilitation center in a medical center in Taiwan and measured their demographic data, cognitive performance, and physical fitness, metabolic profiles and sleep parameters. They were divided into two groups according to clinical ...

The tip leakage vortex (TLV) has aroused great concern for turbomachine performance, stability and noise generation as well cavitation erosion. To better understand structures dynamics of the TLV, large-eddy simulation (LES) is coupled with a homogeneous model to simulate flow around NACA0009 hydrofoil given clearance. numerical results are validated by comparisons experimental measurements. de...

background: premature birth is a major cause of infant mortality in developed countries. newborns confined to neonatal intensive care units (nicus) are in a rapid stage of brain development. as such, sleep plays a pivotal role in the proper brain development of newborns. however, this developmental aspect is often disregarded due to the lack of information. aim: this study aimed to evaluate the...

We study the pair correlation of active Brownian particles at low density using numerical simulations and analytical calculations. observe a winged correlation: While accumulate in front an particle as expected, depletion wake consists two wings. In limit soft particles, we obtain closed equation for correlation, allowing us to characterize particular, unveil regimes high activity, where wings ...

BACKGROUND The goal of this research is to use smart home technology to assist people who are recovering from injuries or coping with disabilities to live independently. OBJECTIVE We introduce an algorithm to model and forecast wake and sleep behaviors that are exhibited by the participant. Furthermore, we propose that sleep behavior is impacted by and can be modeled from wake behavior, and v...