Short term forecasts of meteorological parameters (including precipitation) over the oceans is often difficult because of the lack of observations used to initialize the forecast models in these regions. While sea surface temperature (SST) fields derived from satellite and in situ data currently provided to the models provide some large scale information on surface forcing, the small scale grad...

Octreotide is a somatostatin analogue that is widely used for cancer therapy and tumor imaging. Its efficacy in tumors depends mainly on the expression of the somatostatin receptor type 2 (sst 2). Desensitization and down-regulation of sst 2 after agonist exposure can have important consequences for patients under ongoing octreotide therapy because it may induce temporary tumor unresponsiveness...

The dominant pattern of tropical and subtropical North Atlantic sea surface temperature (SST) anomalies simulated in the GFDL coupled ocean-atmosphere model is identified and compared to observations. The spatial pattern and temporal variability of that pattern resemble observational results. On interannual time scales it is shown that anomalous surface heat fluxes, consistent with variations i...

[1] We use elemental ratio (Mg/Ca, Sr/Ca, U/Ca and Ba/Ca) and oxygen isotope data from a Porites lutea coral head collected from offshore Amédée Island, New Caledonia (22 290S, 166 280E) to assess the degree to which changes in these geochemical variables reflect variations in sea surface conditions. We have assessed the robustness of each geochemical proxy by comparing 25 years (1992–1968) of ...

Inhibitory circuitry plays an integral role in cortical network activity. The development of transgenic mouse lines targeting unique interneuron classes has significantly advanced our understanding of the functional roles of specific inhibitory circuits in neocortical sensory processing. In contrast, considerably less is known about the circuitry and function of interneuron classes in piriform ...

Baratta, Michael V., Tyra Lamp, and Melanie K. Tallent. Somatostatin depresses long-term potentiation and Ca signaling in mouse dentate gyrus. J Neurophysiol 88: 3078–3086, 2002; 10.1152/jn.00398.2002. The selective loss of somatostatin (SST)-containing interneurons from the hilus of the dentate gyrus is a hallmark of epileptic hippocampus. The functional consequence of this loss, including its...

The clinical effectiveness of the Kampo medicine Sho-seiryu-to (SST) has recently been demonstrated in a double-blind randomized study of allergic asthma and rhinitis. We investigated the effect of SST on a type 1 allergic model in mice. Ovalbumin (OVA)-induced sneezing and the total and OVA-specific IgE levels were significantly suppressed with SST at 1.0 g/kg, but that of OVA-specific IgG(2a)...

In part 1 of our review on somatostatin (SST) receptor biology in neuroendocrine tumours, the somatostatin receptor (SSTR) as a G-protein coupled receptor (GPCR), and the anti-tumour effects of SST and SSTR post-signalling pathways, were reviewed. To recapitulate, SST is a peptide hormone which acts mainly as an inhibitor in many endocrine systems. SST has five receptor subtypes (SSTR1–5) with ...

Different types the spectrum of photons were studied; they were emitted from the flattening filter of a LINAC Varian 2100 C/D that operates at 15 MV. The simplified geometry of the LINAC head was calculated using the MCNPX code based on the studies of the materials of the flattening filter, namely, SST, W, Pb, Fe, Ta, Al, and Cu. These materials were replaced in the flattening filter to calcula...