The non-natural pyrido[2,3-d]pyrimidine nucleoside F, which pairs preferentially with guanine (G) and adenine (A) within double-helical DNA, recognizes with high selectivity AT base pairs within triple-helical complexes. These observations suggest that F may exist in different tautomeric forms within double-helical and triple-helical complexes. Analysis of the base stacking properties of this e...

Permutation polynomials over a ring of modulo 2w are compatible with digital computers and digital signal processors, and so they are in particular expected to be useful for cryptography and pseudo random number generator. In general, the period of the polynomial should be long in such fields. In this paper, we derive the necessary and sufficient condition which specify one-stroke polynomials w...

BACKGROUND This placebo-controlled study assessed the effects of the once-daily inhaled corticosteroid (ICS) fluticasone furoate (FF) and long-acting beta(2) -agonist (LABA) vilanterol (VI) on early and late asthmatic responses (EAR/LAR) and airway hyper-responsiveness (AHR). METHODS Patients (n = 27) were randomized to FF (100 μg), VI (25 μg), FF/VI (100/25 μg), and placebo for 21 days (four...

I summarize some recent results obtained in collaboration with P. Bouwknegt and K. Pilch on the spectrum of physical states in W 3 gravity coupled to c = 2 matter. In particular, it is shown that the algebra of operators corresponding to physical states – defined as a semi-infinite (or BRST) cohomology of the W 3 algebra – carries the structure of a G-algebra. This G-algebra has a quotient whic...

Background: During intensity modulated radiation therapy (IMRT) technique, theoretically, presence of flattening filter (FF) across the beamline of clinical linear accelerator (linac) is not essential to obtain uniform lateral profiles due to intensity modulation of photon beams by multileaf collimators (MLCs). The aim of this study was to investigate the dosimetrical properties of 18 MV photon...

INTRODUCTION To achieve personal goals in exercise task completion, exercisers have to regulate, distribute, and manage their effort. In endurance sports, it has become very commonplace for athletes to consult task-related feedback on external devices to do so. The aim of the present study was to explore the importance of the presence of this information by examining the influence of the absenc...

1.1 The lifting problem The problem we are concerned with in our lectures and which we shall refer to as the lifting problem was originally formulated by Frans Oort in [17]. To state it, we fix an algebraically closed field κ of positive characteristic p. Let W (κ) be the ring of Witt vectors over κ. Throughout our notes, o will denote a finite local ring extension of W (κ) and k = Frac(o) the ...

A lamp-pumped, 13-W cw Nd:YAG ring laser at 1.064 microm is injection locked using a 40-mW single-frequency diodelaser-pumped Nd:YAG laser as the master oscillator. The phase fidelity of the injected slave to the master is measured using an all-optical technique.

BACKGROUND Single-inhaler fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100/62.5/25 μg has been shown to improve lung function and health status, and reduce exacerbations, versus budesonide/formoterol in patients with chronic obstructive pulmonary disease (COPD). We evaluated the non-inferiority of single-inhaler FF/UMEC/VI versus FF/VI + UMEC using two inhalers. METHODS Eligible p...