Approximately 80% of psoriatic individuals experience pruritus, of varying intensity. This study evaluated the frequency of vulvar itching and burning and its influence on well-being in women with psoriasis. A total of 93 women were included in the study. Psoriasis severity was assessed according to the Psoriasis Area and Severity Index, the intensity of vulvar discomfort by visual analogue sca...

Object: To determine if vulvar melanosis progressed to melanoma over a period of 20 years or more. Methods: In 2010 the hospital records from the Royal Brisbane Hospital Vulvar Clinic between 1976 and 1988 were reviewed and cross checked with the state wide Queensland Centre for Gynaecological Cancer (QCGC) data base to determine if any patient had been lost to follow up and subsequently develo...

Vulvar lymphedema is an uncommon and disabling side-effect of pelvic lymphadenectomy and pelvic radiotherapeutic treatment for invasive genital cancer. Lymphorrhea, a complication of lymphedema, may be extremely distressing for patients due to the requirement to wear sanitary towels and as the pain and loss of elasticity of the vulvar skin and mucosa can cause discomfort during coitus. Surgical...

Stevens-Johnson syndrome (SJS) is a severe drug eruption that presents with fever, along erythema, blisters, and erosion on the skin, oral cavity, eye conjunctiva vulvar mucosa. Here we report case of SJS without skin lesions in an 81-year-old man who underwent tooth extraction at our department due to periodontitis. He developed fever swelling eyelids lips during night visited because symptoms...

Vulvar leiomyomas are extremely rare smooth muscle tumors that easily mistaken for other lesions, as the differential diagnosis must consider a wide spectrum of benign and malignant lesions. We present case 52-year-old woman with three-year history progressive abdominal distension pain an enlarging vulvar mass distorting labia majora causing gait disturbance. Imaging confirmed enormous pelvic o...

MiR-223-5p has been previously mentioned to be associated with tumor metastasis in HPV negative vulvar carcinomas, such as in several other tumor types. In the present study, we hypothesized that this microRNA would be important in vulvar cancer carcinogenesis and progression. To investigate this, we artificially mimicked miR-223-5p expression in a cell line derived from lymph node metastasis o...

Syringoma is a benign eccrine sweat gland tumour affecting mostly females at puberty as multiple soft papules usually 1-2 mm in diameter. The sites of predilection are lower eyelids, cheeks. Syringoma of the vulva is a rare disorder. Only few cases have been reported in the literature. We report here a case of 46-year-old female who presented to gynecology department with vulvar papules associa...

Surgery on vulvar malignancies has become more conservative over the past several decades. A radical vulvectomy with removal of bilateral inguinal lymph nodes en bloc, a mutilating procedure fraught with high complication rates still performed in the 1980s, has become a rarity in today’s practice. This may be partially due to the fact that tumors tend to be diagnosed at earlier stages, thanks t...

A 67-year-old woman who was presented to the gynecologist with a two-month history of heavy vaginal bleeding, after an excisional biopsy of vulvar mass, was diagnosed with the right colon adenocarcinoma metachronous metastasis to the vulva. Pathological examination preliminarily revealed by primary adenosquamous carcinoma of vulva. The original submitting pathologist and gynecologist were conta...

Primary vulvar adenocarcinomas are very rare. We describe the rare case of primary vulvar apocrine adenocarcinoma, a histologically rare subtype of vulvar adenocarcinoma. A 57-year-old Japanese woman presented with an enlarging vulvar mass. A dark-red, hemorrhagic, ulcerated tumor was on the right side of the anterior labial commissure measuring approximately 3.5 × 3.5 cm. Preoperative biopsy s...