نتایج جستجو برای: viral nervous necrosis virus

تعداد نتایج: 701446  

Distemper virus is a Morbillivirus (in the family Paramyxoviridae) that can cause contagious disease in dogs. The virus affects the respiratory, digestive, and nervous systems after transmission. In this study, we reported a case of human infection and involvement with the Distemper virus. A 31-year-old man was diagnosed with clinical signs of Distemper in dogs. After serologic tests on saliva...

Journal: :New Phytologist 2021

Pathogens have evolved various strategies to overcome host immunity for successful infection. Maize chlorotic mottle virus (MCMV) can cause lethal necrosis in maize (Zea mays) when it coinfects with a the Potyviridae family. However, MCMV pathogenicity determinant remains largely unknown. Here we show that P31 protein of is important viral accumulation and essential symptom development. Ectopic...

H Rajabi Memari, M Dadar, M.R Seifi Abad Shapouri , R Peyghan ,

Infectious Pancreatic Necrosis Virus (IPNV) is a member of the family Birnaviridae that has been linked to high mortalities in salmonids. Bacterial based systems as live vectors for the delivery of heterologous antigens offer a number of advantages as vaccination strategies. VP2 is a structural viral protein of IPNV with immunogenicity effects. In this study IPNV was isolated from diseased fry ...

Journal: :The Journal of biological chemistry 2002
Woj M Wojtowicz Michael Farzan John L Joyal Kara Carter Gregory J Babcock David I Israel Joseph Sodroski Tajib Mirzabekov

Alzheimer's disease is characterized by deposition of beta-amyloid peptide (Abeta) into plaques in the brain, leading to neuronal toxicity and dementia. Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system can also cause a dementia, and amyloid deposition in the central nervous system is significantly higher in HIV-1-infected individuals compared with uninfected c...

2013
Yejin Kim Hyemin Kim Seyeon Bae Jiwon Choi Sun Young Lim Naeun Lee Joo Myung Kong Young-il Hwang Jae Seung Kang Wang Jae Lee

L-ascorbic acid (vitamin C) is one of the well-known anti-viral agents, especially to influenza virus. Since the in vivo anti-viral effect is still controversial, we investigated whether vitamin C could regulate influenza virus infection in vivo by using Gulo (-/-) mice, which cannot synthesize vitamin C like humans. First, we found that vitamin C-insufficient Gulo (-/-) mice expired within 1 w...

2015
Andre Barkhordarian April D Thames Angela M Du Allison L Jan Melissa Nahcivan Mia T Nguyen Nateli Sama Francesco Chiappelli

UNLABELLED Viral cellular immune surveillance is a dynamic and fluid system that is driven by finely regulated cellular processes including cytokines and other factors locally in the microenvironment and systemically throughout the body. It is questionable as to what extent the central nervous system (CNS) is an immune-privileged organ protected by the blood-brain barrier (BBB). Recent evidence...

Journal: :The new microbiologica 2008
Marzia Boaretti Giovanna Scalet Roberta Fontana

Cerebrospinal fluid specimens from 226 patients with suspected viral infections of the central nervous system (CNS) were tested by polymerase chain reaction (PCR) to identify the most frequent viruses involved in these infections. A positive PCR result was obtained in 18 patients (7 cases positive for herpes simplex viruses, 5 for enterovirus, 3 for JC virus, 2 for varicella-zoster virus, and 1...

Journal: :Journal of neurovirology 1999
L M Hoffman B T Fife W S Begolka S D Miller W J Karpus

Theiler's murine encephalomyelitis virus is an endemic murine pathogen that induces a demyelinating disease of the central nervous system in susceptible mouse strains. The disease is characterized by central nervous system mononuclear cell infiltration and presents as chronic, progressive paralysis. The expression of CC and C-x-C chemokines in the central nervous system of Theiler's murine ence...

2005
Fredrik Aronsson Charlotta Lannebo Martin Paucar Johan Brask Krister Kristensson

Epidemiological studies have indicated an association between inuenza A virus infections during fetal life and neuropsychiatric diseases. To study the potential for inuenza A virus infections to cause nervous system dysfunctions, we describe a mouse model using intranasal instillation of the mouse neuroadapted inuenza A/WSN/33 strain in pregnant mice. Viral RNA and nucleoproteinwere detected...

2013
Tal Kramer Lynn W. Enquist

Alphaherpesviruses are pathogens that invade the nervous systems of their mammalian hosts. Directional spread of infection in the nervous system is a key component of the viral lifecycle and is critical for the onset of alphaherpesvirus-related diseases. Many alphaherpesvirus infections originate at peripheral sites, such as epithelial tissues, and then enter neurons of the peripheral nervous s...

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