In this study, the anti-osteoarthritis effects of Cynanchum wilfordii, Phlomis umbrosa, and Angelica gigas extract (CPAE), observed and confirmed in previously clinical studies were further investigated by in vitro and in vivo studies. Anabolic biomarkers related to healthy cartilage maintenance, such as aggrecan, type II collagen α-1 (Col2a1), sex determining region Y-box-9 (Sox-9), and catabo...

Calcium, magnesium, copper, iron and zinc are stored in hens’ egg yolk and, except for copper, the majority of these minerals are located in egg yolk granules (Table 1). Presumably, up to 90% calcium, magnesium, iron and zinc are firmly bound in the phosvitin-lipovitellin complex of granules (GREENGARD et al., 1964; TABORSKY, 1980; TUPPER et al., 1954). As was discussed by Richards, copper ions...

Hormone replacement therapy (HRT) consists of highly effective prescription medications for treating menopausal symptoms; however, these agents have exhibited side effects including the risk of estrogen-induced carcinogenesis. Therefore, interest in phytotherapy-based materials as a natural source of alternatives to estrogen therapy has increased. However, some of these herbal medicines have be...

coat protein gene confers cross-protection in transgenic tobacco and tomato plants. EMBO J. 6:1181-1188. Vaek, M., A.S. Reynaerts, H. Hofte, S. Jansens, M. de Beucketer, C. Dean, M. ZaBeau, M. van Montagu, and J. Leemans. 1987. Transgenic plants protected from insect attack: Nature (London) 328:33-37. van der Krol, A.R., P.E. Lenting, J. Veenstra, I.M. van der Meer. R.E. Koes, A.G.M. Gerats, J....

A method coupling high-performance liquid chromatography with hybrid ion trap time-of-flight mass spectrometry (TOFMS) using an electrospray ionization source was firstly used to characterize ten major pregnane glycosides including one novel compound auriculoside IV from the roots of Cynanchum auriculatum Royle ex Wight. In the MS/MS spectra, fragmentation reactions of the [M+Na]+ were recorded...

Ongoing dialogues between customers and web-based virtual advisors (e.g., Kelley Blue Book’s Auto Choice Advisor) are an untapped source of marketing research data for new product opportunities based on new combinations of customer needs. These data provide the scale necessary for complex products (148 trucks and 129 customer needs in our application). The tracking data are available at little ...

LEGER, L., LENRIOT, J.P. & LEMAIGRE, G. (1968) L'hypertension et la stase portales segmentaires dans les pancr6atites chroniques. Journal de Chirurgie (Paris), 95, 599. MCCURDY, D.K., FREDERIC, M. & ELKINGTON, J.R. (1968) Renotubular acidosis due to amphotericin B. New England Journal of Medicine, 278, 124. NEW, P.S. & WELLS, C.E. (1965) Cerebral toxicity associated with massive intravenous pen...

BACKGROUND Pestiviruses in general, and Bovine Viral Diarrhea (BVD) in particular, present several potential targets for directed antiviral therapy. MATERIAL AND METHODS The antiviral effect of Cynanchum paniculatum (Bge.) Kitag (Dog strangling vine: DS) extract on the bovine viral diarrhea (BVD) virus was tested. First, a cytotoxicity test in MDBK (Madin-Darby bovine kidney) cells was done w...

Cynanchum wilfordii is one of most widely used medicinal plants in Oriental medicine for the treatment of various conditions. In the present study, we isolated cynandione A (CA) from an extract of Cynanchum wilfordii roots (CWE) and investigated the effects of CA on the expression of inducible nitric oxide synthase (iNOS) and pro-inflammatory cytokines in lipopolysaccharide (LPS)-induced BV-2 m...

The International Committee on Nomenclature of Viruses. Progress report from the President In vitro Transformation of Primary and Continuous Rat Fibroblasts by Rous Sarcoma Virus (SCHMIDT-RU'PPIN). By N. SHARON . . . . . . . . . . . Interferon Response to Sendal and Rubella Viruses in Human Foetal Cultures, Leucocytes and Placental Cultures. By J. E. BANATVALA, J. E. POTTER and J. M. BEST . . ....