The ATP requirement during RNA transcription by the RNA-dependent RNA polymerase associated with purified vesicular stomatitis virus was studied during chain initiation and chain elongation steps. Initiation of transcription in vitro has an apparent Km for ATP of approximately 500 micron, whereas the apparent Km for ATP during chain elongation is almost identical with those for the other three ...

Lupi et al. present, on p. 80–81, an interesting case report of dyshidrosiform palmo-plantar pemphigoid. They describe a 20-year-old man who had had itchy vesicles on his palms and soles for 1 year. Histologically, a subepi-dermal vesicle was seen, and direct immunofluorescence showed continuous linear deposition of IgG and C 3 at the dermal-epidermal junction. An enzyme-linked immuno-sorbent a...

Dopamine neurons in the ventral tegmental area (VTA) play an important role in the motivational systems underlying drug addiction, and recent work has suggested that they also release the excitatory neurotransmitter glutamate. To assess a physiological role for glutamate corelease, we disrupted the expression of vesicular glutamate transporter 2 selectively in dopamine neurons. The conditional ...

Electron micrographs of a purified succinate and DPNH oxidase system prepared from heart muscle reveal that it has a vesicular appearance and is membranous in nature. In keeping with its vesicular appearance is the fact that light scattering by this preparation shows marked changes as the molarity of the suspending medium is altered. Treatment of this preparation with 0.5 per cent deoxycholate ...

Introducción. La neoplasia papilar intracolecística se caracteriza por el crecimiento exofítico del epitelio de la vesícula biliar hacia su interior. Casos clínicos. Presentamos dos casos clínicos con masa vesicular a quienes les realiza colecistectomía, dado riesgo que esos hallazgos sean pólipos vesiculares malignos. anatomía patológica certifica corresponden una intracolecística. Discusión. ...