We have previously reported isolated cases of anatomical and functional closure of ventricular septal defects in tricuspid atresia. To study this phenomenon further, clinical, angiographic, and pathological findings in 20 consecutive cases of tricuspid atresia were reviewed. Sixteen cases were found to have normally related great arteries (type I) and 4 had transposition (type II). In 6 of thes...

Work-function curves relating systemic ventricular end-diastolic pressure (EDP) to minute work index (MWI) were used to assess ventricular performance in eight patients with tetralogy of Fallot (TOF), five patients with ventricular septal defect (VSD), and nine patients with d-transposition of the great arteries (TGA). All patients underwent repair when they were younger than 18 months of age a...

T HE PROBABILITY that postnatal spontaneous closure of ventricular septal defect occurs with some frequency has been evident to clinicians for a number of years. This postulate is based upon the presence of characteristic murmurs in childhood which disappear with the growth and development of the patient.1-7 Convincing evidence of spontaneous functional closure of ventricular septal defects is ...

A 20-year-old female had undergone definitive surgical repair for pulmonary atresia with intact ventricular septum soon after birth. She was referred to our institution with the chief complaint of clubbing fingers. A thorough examination revealed platypnea-orthodeoxia syndrome due to an interatrial right-to-left shunt through a secundum atrial septal defect. Percutaneous closure with an Amplatz...

Background: Congenital heart disease is the most common type of maternal abnormality and is the leading cause of mortality in the first year of life. The aim of this study was to determine the epidemiological and related factors of congenital heart disease (CHD) in children referred to the pediatric heart clinic of Vali-e-Asr Hospital of Birjand, Iran. <e...

BACKGROUND The decision whether to close the ventricular septal defect at the time of unifocalization in patients with pulmonary atresia, ventricular septal defect, and major aortopulmonary collaterals may be difficult. The purpose of this study was to develop morphologic and physiologic methods to aid in deciding whether to close the ventricular septal defect in patients undergoing one-stage u...

Surgical closure of ventricular septal defect is safe, however, the inherent risks associated with cardiopulmonary bypass and the potential early and late postsurgical complications including complete heart block, arrhythmias, postpericardiotomy syndrome, and rare deaths have led physicians to prefer transcatheter occlusion technique for closure of such defects. The use of Amplatzer muscular ve...