Patient-ventilator synchrony and patient comfort are assumed to go hand in hand, yet few studies provide support for this common sense idea. In reality, synchrony between the patient and ventilator is complex and can be affected by the ventilator settings, type of ventilator, patient-ventilator interface, and sedation. Inspections of airway pressure and flow waveforms are reliable methods for d...

Historically, the relationship between the ventilator circuit and pulmonary infection was accepted as fact, without any scientific evidence. Hence the term, "ventilator"-associated pneumonia. Recent evidence, however, has demonstrated that the major sources of pneumonia in the ventilated patient are colonization of the gastrointestinal tract, with subsequent aspiration around the endotracheal t...

During this COVID-19 pandemic time, an unprecedented number of patients with severe respiratory illness require intensive care units (ICUs) under mechanical ventilation (MV) for sustaining life. Patient–ventilator asynchrony (PVA) is very common, and it occurs due to the mismatch between normal variability patients’ breathing patterns ventilator parameters. Asynchronies during invasive are caus...

We reviewed all patient safety incidents reported to the UK National Patient Safety Agency between August 2006 and February 2007 from intensive care or high dependency units. Incidents involving equipment were then categorised. A total of 12 084 incidents were submitted from 151 organisations (median (range) 40 (1-634) per organisation). Of these, 1021 incidents were associated with use of equi...

BACKGROUND AND PURPOSE Aspiration of secretions containing bacterial pathogens into the lower respiratory tract is the main cause of ventilator-associated pneumonia. Endotracheal tubes with subglottic secretion drainage can potentially reduce this and, therefore, the incidence of ventilator-associated pneumonia. New evidence on subglottic secretion drainage as a preventive measure for ventilato...

background: ventilator-associated pneumonia (vap) is a type of nosocomial pneumonia which develops more than 48 hours after endotracheal intubation. early recognition and treatment of vap is important, since timely and appropriate management can be lifesaving. objectives: this study aimed to determine the antimicrobial susceptibility pattern of microorganisms causing vap in the intensive care u...

background ventilator- associated pneumonia (vap) continues to complicate the course of 8-28 % patients receiving mechanical ventilation. the mortality rate for vap is high, ranges from 24-50% and can reach 76% in some specific settings or when lung infection is caused by high risk pathogens. the etiologic agents widely differ according to the population of patients in an intensive care unit, d...

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background: ventilator-associated pneumonia (vap) is the most prevalent and lethal form of nosocomial infections in the icu and oral disinfection is a nursing measure to prevent this condition. aim: this study aimed to evaluate the effect of oronasal versus oral disinfections with chlorhexidine on the clinical criteria for diagnosis of vap. method: this randomized clinical trial was conducted o...