AIM To elicit problem statements describing the consequences of vision impairment as a first step towards the development of a vision related quality of life instrument for use in India METHODS 46 focus groups were conducted in three regions of India. Separate focus groups were held for men and women and according to disease categories: cataract (24), glaucoma (six), diabetic retinopathy or m...

There is a paucity of research exploring barriers to non-oral medicines administration in paediatric patients; however, these undoubtedly influence medicines adherence. Studies conducted with healthcare professionals have identified various issues with the administration and acceptance of non-oral medicines and devices (Venables et al., 2012; Walsh et al., 2015). EMA (2014) guidelines specify t...

[1] Antarctic Bottom Water (AABW), the densest water in the global overturning circulation, has warmed in recent decades, most notably in the Atlantic. Time series recorded within the boundary currents immediately upstream and downstream of the most significant outflow of AABW from the Weddell Sea indicate that raised outflow temperatures are synchronous with stronger boundary current flows. Th...

This paper argues that the contribution of trade preferences to economic development needs to be reappraised in light of the growth of globalised trade in manufactures. Trade preferences may be able to act as a catalyst for manufacturing exports, leading to rapid growth in exports and employment. To do so, preferences need to be designed to be consistent with international trade in fragmented ‘...

Percutaneous venous and retrograde arterial catheterization by the Seldinger technique (Seldinger, 1953), or its modification, is a routine procedure in many cardiovascular diagnostic and research laboratories. The incidence and nature of complications after these procedures vary from one group of investigators to another. Reports and reviews of such complications are available (Peirce, I95I; P...

This paper analyzes the genericity of bifurcations of one-parameter families of smooth (C1) vector …elds that are embedded in an underlying multidimensional parameter space. Bifurcations with crossing equilibrium loci are called “split bifurcations.”They include, for example, the pitchfork bifurcation and the transcritical bifurcation in one-dimensional systems. In a regular parameter space whe...

Condition-specific health status measures are commonly used as outcome measures in clinical trials and to assess patient progress in routine clinical practice. The expert panel that met to discuss this special issue of Spine recommended that, when possible, a condition-specific measure for back pain should be chosen from two widely used measures, the Roland–Morris Disability Questionnaire (RDQ)...