Using an accurately calibrated flowmeter in the descending thoracic aorta of the dog, a study was made of alterations in aortic flow patterns following intravenous and intra-arterial injections of vasoactive drugs. When injected distal to the flowmeter, vasopressors caused marked backflow while vasodilators raised the level of the lowest portion of the pulsatile flow curve. When injected into t...

A ouabain-sensitive, Mg-dependent, Na, K-stimulated adenosinetriphosphatase (ATPase) isolated from canine mesenteric arteries was activated by the following vasodilators: hydralazine, diazoxide, PGE,, PGE,, PGA,, and minoxidil. Epinephrine, norepinephrine, and isoproterenol also stimulated the ATPase, but PGF,Q was ineffective. Since these vasodilators activate the adenylate cyclase of vascular...

BACKGROUND Radial artery spasm is a common hinderance during transradial approaches for neuroangiography. Ways of alleviation have been described, including patient sedation, local lidocaine, or even prophylactic administration intra‐arterial vasodilators. METHODS We present case wedged catheter attributable to radial spasm, which failed all conventional methods relieve spasm. RESULTS The was u...