We suggest a new approach to peripheral vascular bypass surgery planning based on solving the one-dimensional (1D) governing equations of blood flow in patient-specific models. The aim of the present paper is twofold. First, we present the coupled 1D-0D model based on a discontinuous Galerkin method in a comprehensive manner, such as it becomes accessible to a wider community than the one of ma...

Bypass surgery is one of the most frequently used strategies to revascularize tissues downstream occlusive atherosclerotic lesions. For venous bypass surgery the great saphenous vein is the most commonly used vessel. Unfortunately, graft efficacy is low due to the development of vascular inflammation, intimal hyperplasia and accelerated atherosclerosis. Moreover, failure of grafts leads to sign...

Aggressive treatment of ischemia of the lower extremities has decreased the number of amputations in both diabetic and nondiabetic patients; combined vascular reconstruction and microvascular free-flap transfer has been used to improve distal perfusion and cover large tissue defects caused by the critical limb ischemia during the past 30 years. We present our experience with a 71-year-old diabe...

OBJECTIVE The aim of this study was to assess the coronary vascular resistance (CVR) and to analyze the flow differences through grafts in coronary artery bypass graft surgery. METHODS Between 17 June and 15 July 2005, we assessed the coronary vascular resistance profile in 10 patients undergoing coronary artery bypass graft surgery by grafting a section of saphenous vein and checking CVR dir...

AIM Vascular leakage following cardiopulmonary bypass contributes to morbidity. Angiopoietin-1 and -2 are biomarkers of endothelial dysfunction. Our aim was to characterize Ang-1 and -2 association with clinical characteristics and outcomes. METHODS Observational cohort study measuring Ang-1/-2 with a panel of cytokines in adults undergoing cardiopulmonary bypass. RESULTS Ang-2 levels incre...

cardiovascular surgery, pulmonary embolism remains the most serious postoperative complication. All efforts should be directed at eliminating the factors that contribute to its incidence. Recently, there has been a revival of interest in its treatment after Cooley and BealI1 reported the first successful pulmonary embolectomy using cardiopulmonary bypass in 1961. Around the same time hyperbaric...

tory distress syndrome; CI cardiac index; CPB cardiopulmonary bypass; CPDA citrate phosphate dextrose adenine; EF = ejection fraction; IMA internal mammary artery; LAD = left anterior descending artery; LE lung edema; LVSWI = left ventricular stroke work index; PCWP pulmonary capillary wedge pressure; PVR pulmonary vascular resistance; RCA right coronary artery; RVSWI right yentricular stroke w...

Iatrogenic vascular injury during lumbar disc surgery is a rare but serious complication. This paper reports a patient who sustained an injury to the iliac artery while undergoing intervertebral disc surgery at the lumbar region. He suffered from massive bleeding and shock. An urgent laparatomy was performed under cardiopulmonary bypass, and the vascular injuries were repaired successfully. Thi...

The effects of halothane and diethyl ether on pulmonary vascular resistance and the pulmonary vasoconstrictor response to alveolar hypoxia were studied in the innervated perfused cat lung. A left and right heart bypass technique was used to allow perfusion of the lungs at constant flow. Neither anaesthetic agent caused a significant change in pulmonary vascular resistance but both agents caused...