A 51-year-old woman with CREST syndrome (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) developed stepwise progressive focal neurological deficits without zoster rash. Multifocal ischemic infarcts were seen on magnetic resonance imaging, and cerebral angiography revealed focal stenosis of arteries affecting the intracranial circulation. A brain biopsy...

Concurrent reactivation of herpes simplex and varicella zoster viruses is rare. Here, we describe the case of an elderly patient with herpes labialis and herpes zoster manifesting as a right-side facial eruption with vesicles and crusting. The loop-mediated isothermal amplification (LAMP) assay demonstrated the presence of both herpes simplex virus type 1 and varicella zoster virus in swab samp...

An epizootic of simian varicella occurring in a colony of Erythrocebus patas monkeys was studied serologically by using radioimmunoassay and neutralization tests against (i) a virus strain isolated from an animal that died during the epizootic, (ii) a simian varicella virus strain from an earlier outbreak of simian varicella-like disease at another facility, and (iii) human varicella-zoster vir...

Varicella (chicken pox) is a highly contagious disease which is caused by Varicella Zoster Virus (VZV), a ubiquitous human α herpes virus. Nosocomial varicella in hospital employees can be costly to the hospital and disruptive to patient care. This case report describes an occupationally related outbreak of chickenpox in hospital staff and the lessons which were learnt by the hospital during th...

Varicella-zoster virus (VZV), the cause of chickenpox and shingles, is a pathogen in retreat following the introduction of mass vaccination in the United States in 1995. The live attenuated Oka vaccine, which is safe and immunogenic, gives good protection against both varicella and zoster in the short to medium term. It has undoubtedly been highly effective to date in reducing all forms of vari...

TOPIC The incidence and morbidity of herpes zoster (HZ) and HZ ophthalmicus (HZO), and the potential impact of varicella vaccine on their epidemiology. CLINICAL RELEVANCE Herpes zoster affects 20% to 30% of the population at some point in their lifetime; approximately 10% to 20% of these individuals will have HZO. METHODS The peer-reviewed literature published from 1865 to the present was r...

Eosinophilic dermatosis of hematologic malignancy is a rare papulovesicular eruption that presents in patients with hematoproliferative disorders, particularly chronic lymphocytic leukemia. A 59-year-old woman with chronic lymphocytic leukemia who developed eosinophilic dermatosis of hematologic malignancy mimicking varicella zoster infection is described. PubMed database was searched with the ...

Varicella zoster virus can infect the trigeminal ganglion, but viral infection is not frequently considered as a cause of trigeminal neuralgia. This is a case of a woman whose trigeminal neuralgia remitted after being treated with valacyclovir for a thoracic zoster rash and later resolved entirely following administration of the zoster vaccine. Successful treatment of trigeminal neuralgia with ...

Varicella zoster virus (VZV) is well known for its neurotropism, primary infection and reactivation after variable latency periods. After from spinal or cranial nerve ganglia, viruses can affect the central nervous system vasculature via transaxonal migration followed by transmural spread adventitial layer to intima. Stroke occur following VZV (varicella) (zoster). These infectious vasculitides...

Definition Varicella-zoster virus (VZV), also known as Human Herpes Virus III (HHVIII), is a member of the herpes virus group. As all the other viruses from this group, VZV can manifests itself as a recurrent infection. After entering the body and causing primary infection, varicella-zoster virus remains latent in the neurons of sensory ganglion, especially dorsal roots of ganglion of the spina...