The vagus nerve projects to a well-defined neural circuit via the nucleus tractus solitarii (NTS) and its stimulation elicits wide range of metabolic, neuromodulatory, behavioral effects. Transcutaneous (tVNS) has been established as promising technique non-invasively alter brain function. However, precise dynamics elicited by tVNS in humans are still largely unknown. Here, we performed fMRI wi...

The electrocardiographic records taken during vagus stimulation by pressure from children suffering with chronic heart disease have shown that the stimulation of the vagi in these cases is strikingly effectual. In some of the cases, a definite difference was demonstrated between the action of the right and left vagi. The control of the rate of the heart-beat seemed to predominate usually in the...

Vagus nerve stimulation (VNS) has been used since 1997 for treatment of drug-resistant epilepsy. More recently, an off-label use of VNS has been explored in animal models and clinical trials for treatment of a number of conditions involving the innate immune system. The underlying premise has been the notion of the cholinergic antiinflammatory pathway (CAP), mediated by the vagus nerves. While ...

Backgrounds: Injury to the vagus nerve or one of its branches during carotid endarterectomy can result in vocal fold paralysis but the exact mechanism of injury responsible for vocal fold paralysis after carotid endarterectomy is unclear. Aims: This study was performed to identify potential predictors of vagus nerve injury and obtain feedback by application of intraoperative continuous vagus ne...

Inflammatory bowel disease (IBD) is defined as a chronic inflammatory-mediated that causes ulceration and inflammation in the gastrointestinal tract. Among most patients, course of repeatedly shows intermittent exacerbations alternating remissions. However, despite various therapeutic options to relieve symptoms, such corticosteroids, TNF-α inhibitors, antibiotic drugs, there no known cure for ...

Background & objective: Low back pain is a common problem, especially in the young and middle-aged working people, often very resistant to conventional management. We evaluated impact of transcutaneous auricular vagus nerve stimulation (tVNS), applied conjunction with an exercise treatment program, on disability chronic low patients.
 Methodology: The study was conducted from June Octo...

Abstract Background: Vagus nerve stimulation (VNS) has been explored as an adjunct treatment for neurological disorders, such epilepsy, chronic migraine, pain, and depression, well its potential modulation of the immune response. A non-invasive form VNS is transcutaneous auricular (aVNS). The combination animal models with brain imaging may lead to a better understanding mechanisms. aim this st...