Erdely, Aaron, Gary Freshour, and Chris Baylis. Resistance to renal damage by chronic nitric oxide synthase inhibition in the Wistar-Furth rat. Am J Physiol Regul Integr Comp Physiol 290: R66–R72, 2006; doi:10.1152/ajpregu.00444.2005.—Chronic nitric oxide synthase inhibition (NOSI) causes chronic kidney disease (CKD) in the Sprague Dawley (SD) rat. We previously showed that the Wistar-Furth (WF...

BACKGROUND Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a method to monitor the effect and the safety of dabigatran is not currently available. The Global Thrombosis Test (GTT) is a novel method to assess both clot forma...

BACKGROUND To compare wavefront (WF)-guided and WF-optimized laser in situ keratomileusis (LASIK) in hyperopes with respect to the parameters of safety, efficacy, predictability, refractive error, uncorrected distance visual acuity, corrected distance visual acuity, contrast sensitivity, and higher order aberrations. METHODS Twenty-two eyes of eleven participants with hyperopia with or withou...

BACKGROUND Children in the United States do not consume the recommended amounts of fruit. The economic and dietary consequences of meeting the shortfall in fruit consumption have not been evaluated. METHODS Analyses were based on a nationally representative sample of 4-18 year-old children (n = 2,647) from the 2009-2010 National Health and Nutrition Examination Survey (NHANES). The shortfall ...

To effectively manage water resources in agricultural production, it is necessary to understand the spatiotemporal variation of the water footprint (WF) and the influences of agricultural inputs. Employing spatial autocorrelation analysis and a geographically weighted regression (GWR) model, we explored the spatial variations of the WF and their relationships with agricultural inputs from 1998 ...

If the number of users within a workflow management system (WFMS) increases, a central workflow server (WF– server) and a single local area network (LAN) may become overloaded. The approach presented in this paper describes an execution environment which is able to manage a growing number of users by adding new servers and subnets. The basic idea is to decompose processes into parts which are c...

We consider Friedmann cosmologies with minimally coupled scalar field. Exact solutions are found, many of them elementary, for which the scalar field energy density, ρf , and pressure, pf , obey the equation of state (EOS) pf = wfρf . For any constant |wf | < 1 there exists a two-parameter family of potentials allowing for such solutions; the range includes, in particular, the quintessence (−1 ...

is an equally efficacious alternative to urinary derived FSH, Menopur®. One differences between these products is their delivery devices; Gonal f® is provided as a multidose pen, Menopur® in vials or multidose preparation, and Bemfola® as a fixed dose pen. The aim of this study was to determine the impact of delivery device on drug wastage and associated cost. Methods: A retrospective analysis ...

Over the last decades, Morocco has been facing increasingly severe water scarcity. To quantify use in Morocco, we refer to footprint (WF) concept, including both direct and indirect use. WF considered covers internal exported virtual (VW). We used input-output structural decomposition analysis (SDA) quantitatively analyze drivers of changes Morocco’s sectoral from 1995 2015. The mechanisms gove...

Chronic nitric oxide synthase inhibition (NOSI) causes chronic kidney disease (CKD) in the Sprague Dawley (SD) rat. We previously showed that the Wistar-Furth (WF) rats are resistant to several models of CKD and maintain renal nitric oxide (NO) production compared with SD rats, whereas low-dose NOSI caused progression of CKD in WF rats. Here, we evaluate the impact of high-dose chronic NOSI in ...