Urinary tract infection is one of the most common bacterial infections of human. The most common agent of urinary tract infection is Escherichia coli . This study aims to determine the prevalence of uropathogenic E. coli urinary infection in human with different antimicrobial resistance, and quantitive and qualitative study of siderophore production and their association with the ability to cau...

Background & Aims: Urinary tract infection (UTI) is one of the most frequently acquired bacterial infections caused by a large genetically heterogeneous group of Escherichia coli which are called uropathogenic E. coli (UPEC). Cystitis and pyelonephritis are two most common symptoms seen in patients with UTI. The genetic diversity of this organism has hampered the identification of UTI strains a...

Adherence of uropathogenic Escherichia coli to host tissue is required for infection and is mediated by fimbriae, such as pyelonephritis-associated pili (Pap). Expression of P fimbriae is regulated by phase variation, and to date, phase transition frequencies have been measured only for pap regulatory region constructs integrated into the E. coli K-12 chromosome. The aim of this work was to mea...

There are many different bacterial infections in the world that patients are suffering from and research teams are trying to find suitable ways to prevent and treat them. Urinary Tract Infections (UTIs) are most important infections in the world , and they are more common among women because vaginal cavity is near to urethral opening. The aim of this study is cloning of synthetic gene include a...

Escherichia coli is a widespread bacterium encompassing a variety of strains, ranging from highly pathogenic strains, causing worldwide outbreaks of severe diseases to avirulent, well characterized safe laboratory strains. This study evaluated the prevalence and antibiogram profiles of E. coli pathotypes isolated from the Kat River and Fort Beaufort abstraction water. A total of 171 out of 278 ...

Escherichia coli is one of the most frequent causes of extra-intestinal diseases including urinary tract infections (UTI). E.coli is the most frequent urinary pathogen isolated from 50% 90% of all uncomplicated urinary tract infections. (Steadman and, Topley, 1998). It is now recognized that there are subsets of faecal E. coli , which can colonize periurethral area, enter urinary tract and caus...

Strains of uropathogenic E. coli are responsible for approximately 90% of community-acquired, uncomplicated cystitis, and fimbriae represent the adhesive factors enabling E. coli to be anchored to uroepithelial cells in the first step of the infectious process. Recently, a few studies have shown that a correlation between the consumption of cranberry (Vaccinium macrocarpon) and prevention of UT...

Lactobacilli play a protective role against pathogens in the urogenital tract by a combination of multiple mechanisms, not fully understood until now. The purpose of the present paper was to study whether live, heat killed or sonnicated cells of Lactobacillus fermentum are able to protect against the challenge of uropathogenic Escherichia coli in the urinary tract of mice as experimental model....

1Department of Pathology and Microbiology, Faculty of Medicine, University of Jordan, Amman, Jordan. Received: 27/01/03; accepted: 06/05/03 ABSTRACT We investigated antimicrobial resistance patterns and plasmid profiles of uropathogenic Escherichia coli isolates from inpatients and outpatients at Jordan University Hospital in 2000 and 2001. E. coli accounted for 32.4% and 37.4% of all isolates ...

Copper plays a dual role as a nutrient and a toxin during bacterial infections. While uropathogenic Escherichia coli (UPEC) strains can use the copper-binding metallophore yersiniabactin (Ybt) to resist copper toxicity, Ybt also converts bioavailable copper to Cu(II)-Ybt in low-copper conditions. Although E. coli have long been considered to lack a copper import pathway, we observed Ybt-mediate...