BACKGROUND antenatal variant of Bartter syndrome is characterized by a history of polyhydramnios, premature birth, metabolic alkalosis, hypokalemia, polyuria and renal salt wasting. In this report we present a premature female baby with antenatal Barter syndrome who had three episodes of urinary tract infection (UTI), without evidence for congenital anomaly of the kidneys or urinary tract. ME...

Congenital anomalies of the kidney and urinary tract (CAKUT) account for more than 50% of abdominal masses found in neonates and involve about 0.5% of all pregnancies. CAKUT has a major role in renal failure, and increasing evidence suggests that certain abnormalities predispose to the development of hypertension and cardiovascular disease in adulthood. To understand the pathogenesis of human r...

Down syndrome (DS), the most common chromosomal abnormality with a prevalence of 1 case per 600 live births (Dennis & Marder,2001), has many manifestations that can affect multiple organ systems (American Academy of Pediatrics Comittee on Genetics, 2001; Kallen et al., 1996) including urological abnormalities which have been recognized throughout urinary tract (Ariel et al., 1991; Berg et al.,1...

PURPOSE To report the outcomes of laparoscopic surgery combined with endourological assistance for the treatment of renal stones in patients with associated anomalies of the urinary tract. To discuss the role of laparoscopy in kidney stone disease. MATERIALS AND METHODS Thirteen patients with renal stones and concomitant urinary anomalies underwent laparoscopic stone surgery combined with anc...

OEIS complex is one of the congenital anomalies not compatible with life. It comprises of omphalocele, exstrophy of the cloaca, imperforate anus and spinal defects with incidence of 1:100,000 live births. It can be associated with other anomalies of urinary tract, genital tract, skeletal defects variably. Diagnosis can be done prenatally by ultrasonography. We present a case of OEIS complex wit...

Meningomyelocele (MMC) is the most common form of neural crest closure defect and may be associated with dysfunction and malformations of multiple organs including urinary tract. It affects as many as 2-4 in 1000 live births, however there are no epidemiological studies available from India. Anatomical and neurogenic abnormalities of the urinary tract are known to occur in these patients. Scant...

PURPOSE Williams-Beuren syndrome is a rare multiple anomalies/mental retardation syndrome caused by deletion of contiguous genes at chromosome region 7q11.23. The aim of this work was to determine the frequency and the types of renal and urinary tract anomalies in 20 patients with Williams-Beuren syndrome. METHODS The fluorescence in situ hybridization test using a LSI Williams syndrome regio...

results mean urinary il-1α, il-4, il-6, and il-8 concentrations significantly increased in the acute phase of apn compared to the control group, and decreased following antibiotic treatment. conclusions we recommend routine urinalysis and urine culture for the diagnosis of children with apn. urinary il-4 was a relatively good cytokine for the prediction and treatment-monitoring of children with...

Vesicoureteral reflux, the abnormal flow of urine from the bladder into the ureter, is one of the most common congenital anomalies found in children. The association of vesicoureteral reflux with urinary tract infections and renal scarring has important clinical implications. New insights into pathogenesis and new surgical techniques are changing the approach to the management of this disorder.

A one-year-old child being investigated for urinary tract infection was diagnosed with a multiseptate gallbladder. The patient remains asymptomatic, and investigations demonstrate no associated anomalies. Forty-three cases, including 13 cases in children were identified in the literature. Their presentation and management were reviewed.