A 49-year-old woman visited the clinic because of acute hepatitis and acute kidney injury with decreased urine output presenting microscopic hematuria and proteinuria. An abdominal computed tomography revealed a localized, hypoattenuated lesion in a hepatic lateral segment, and kidney biopsy showed oxalate crystal deposition with tubular necrosis. In addition, the patient׳s 24-hour urinary excr...

Measurement techniques The only technique that is practicable for widespread clinical application is conventional sphygmomanometry with a well maintained mercury sphygmomanometer. Measurement of systolic blood pressure is preferred to diastolic blood pressure because of its greater accuracy and consistency. The choice of the correct cuff is crucial. To cover the age range 0-14 years a minimum o...

Haag and Larson (1) demonstrated in 1942 that in the case of nicotine the extent of urinary excretion of a chemical may be related to the reaction of urine. They emphasized the importance of taking into consideration the dissociation constant of a drug and the relative reabsorbability of the free and dissociated base. Extending these studies to the urinary excretion of quinine in man, Haag, Lar...

OBJECTIVE To assess renal involvement in sick neonates referred to Neonatal Intensive Care Unit (NICU) using standard renal parameters and urinary beta 2 microglobulin (B2M) excretion. DESIGN Descriptive study. SETTING Level II NICU and Nephrology Division of Pediatric Tertiary hospital. SUBJECTS Forty six term sick neonates transferred for neonatal care and forty healthy term neonates wh...

Brain natriuretic peptide (BNP) shares structural and functional similarities to atrial natriuretic peptide (ANP). Although BNP and ANP interact with the same biologically active guanylate cyclase-coupled receptor, recent reports conflict with regard to the biological actions of exogenous BNP in sodium-retaining and edematous states. We studied the biological actions of BNP in normal dogs (n = ...

Previous reports (1-9) have delegated a secondary role to anterior pituitary hormones in the control of aldosterone secretion.' Although hypophysectomy resulted in decreased aldosterone secretion (3) or reduced urinary aldosterone output (2), hyperaldosteronuria, marked sodium (Na) retention and ascites occurred in the absence of the adenohypophysis in dogs with thoracic inferior vena cava cons...

SIR,-Ampicillin,1 phenoxymethylpenicillin,2 and neomycin3 have been shown to decrease urinary oestriol output in normal human pregnancy. We have explored this matter further by employing a new gas chromatographic method4 which enables the four known urinary oestriol conjugates to be measured separately. Six healthy mothers 33-37 weeks pregnant were given 0 5 g of ampicillin orally four tines da...

The prevalence of urinary stone disease in 426 patients who had undergone bowel surgery at the General Infirmary at Leeds from 1958 to 1978 was found by postal questionnaire to be 9.4%. The risk of urinary stone formation was determined from the composition of 24 hour urines from 61 unselected patients, in whom intestinal resections had been performed. There were 27 patients with an ileostomy, ...

OBJECTIVE Intensive care unit survivors and non-survivors have distinct acid-base profiles. The kidney's regulation of urinary electrolytes and the urinary strong ion difference plays a major role in acid-base homeostasis. The aim of this study was to evaluate the potential utility of daily spot urinary electrolyte measurement in acid-base and renal function monitoring. METHODS We prospective...