OBJECTIVE To assess the predictability of outcome and evaluate the factors that may lead to treatment failure in patients with Graves' disease who are treated with a single dose of radioiodine. MATERIALS AND METHODS This is a retrospective study of 123 patients (M: 42; F: 81) with Graves' disease who received radioiodine therapy with a single fixed (10 mCi) dose for hyperthyroidism. Pretreatm...

Increased manganese (Mn) use in manufacturing and in gasoline has raised concern about Mn-induced parkinsonism. Previous research indicated carrier-mediated brain entry but did not assess brain efflux. Using in situ rat brain perfusion, we studied influx across the blood-brain barrier (BBB*) of three predominant plasma Mn species available to enter the brain: Mn2+, Mn citrate, and Mn transferri...

OBJECTIVES The human papillomavirus (HPV) vaccine is safe and efficacious in patients with systemic inflammatory diseases (SID) who have higher rates of persistent HPV infection. We compared HPV vaccine uptake among SID and non-SID patients. METHODS Using a U.S. insurance claims database (2006-2012), we identified individuals 9-26 years with ≥2 SID diagnosis codes ≥7 days apart with ≥12 month...

This study was designed to investigate the correlation between expression levels of cysteine aspartic protease-3 (caspase-3) and B-cell lymphoma gene-2 (Bcl-2) proteins in alveolar lavage fluid and the prognosis of infants with neonatal respiratory distress syndrome (RDS). A total of 150 infants with neonatal RDS undergoing alveolar lavages were divided into four groups: RDS1 (group A, n=42), R...

The presence of adrenergic regulation of estradiol uptake in rat uterus was studied by using alpha- and beta-adrenergic blockers in normal or Ca2+-free Tyrode's solution at 30 degrees C in vitro. Cyclic GMP content was also investigated under these conditions. By the stimulation with noradrenaline (4 X 10(-7) M), Ca2+-dependent 3H-estradiol uptake was increased in both cytosol and nuclear fract...

OBJECTIVE The aim of this study was to assess the utility of 201Tl SPECT in the differential diagnosis of intracranial tumors and to determine the relationship between 201Tl uptake and histological types. METHODS Thirty-eight patients (19 males and 19 females) with thirty-eight brain tumors were evaluated with 201Tl-SPECT. The early and delayed 201Tl uptake ratio was calculated, and the reten...

The effect of solar radiation on a natural bacterial population from the Chesapeake Bay was evaluated from measured changes in numbers of organisms engaged in amino acid uptake. From July through May, freshly collected water samples were exposed in quartz containers to 3.5 h of total sunlight both with and without UV-absorbing filters. Water samples were subsequently incubated with tritiated am...

The effect of diazepam on thyroid function tests was examined in 12 euthyroid patients requiring the drug for psychiatric reasons and in six patients with thyrotoxicosis. Assessment was made before and after four weeks' therapy.There was no significant difference in results from tests of thyroid iodide trapping and binding (thyroid radioiodine uptake, thyroid clearance, and absolute iodine upta...

heavy metals contamination is a major environmental problem which requires immediate human attention. the use of plant species to remove pollutants from soils, generally defined as phytoextraction. in order to evaluate phytoextraction of contaminated soils, a pot experiment conducted using two plants barley, canola three kinds of heavy metals (cd, pb, ni) with 3 levels in a completely randomize...

poinsettia as an ornamental pot plant is widely grown in peat-based substrates with high phosphorus (p) fertilization. the aim of current study was to evaluate the p demand of poinsettia according to its depletion ability during the growth stages by using a mechanistic simulation model. for this purpose, rooted poinsettia cuttings were grown in the medium with 80: 20 (v: v %) peat+ mineral comp...