BACKGROUND Liposarcomas are among the most common sarcomas of adult life. Pleomorphic liposarcoma, characterized by pleomorphic lipoblasts, is the rarest subtype. To our knowledge only three cases of pleomorphic liposarcoma of the foot or ankle have been reported so far. CASE PRESENTATION A 71-year-old female presented with a large growing mass on the dorsum of her right foot. Computed tomogr...

In the 2020 World Health Organization classification, for first time, three new groups of tumors were formalized, initially isolated from group undifferentiated round cell sarcomas, so-called Ewing-like namely sarcoma with BCOR genetic alterations, CIC-rearranged and sarcomas EWSR1 gene rearrangement atypical (non-ETS family) partner genes. This review will focus on which be illustrated by one ...

RATIONALE Primary undifferentiated pleomorphic sarcoma is extremely rare in the thyroid, and can be easily misdiagnosed as anaplastic thyroid cancer. PATIENT CONCERNS We present a case of a 71-year-old woman who presented with a rapidly growing painless mass in the neck. DIAGNOSES-INTERVENTIONS-OUTCOMES Computed tomography showed a large hypointense mass with hyperdense areas involving whol...

  Primary sarcomas of the kidney are exceptional. Among renal sarcomas, leiomyosarcoma is the most common histologic subtype amounting to 50-60% of all cases. The tumor usually arises from either the renal capsule or smooth muscle tissue in the renal pelvic wall. In this paper, we report a patient with leiomyosarcoma of the kidney presented with non-specific abdominal pain and a palpable mass....

Primary penile sarcoma is an extremely rare condition. The incidence of penile sarcoma is described as 0.6 to 1 out of 100,000 patients in developed countries, and leiomyosarcoma is the predominant histological type. Given such a low incidence, treatment for this condition is very controversial. The authors could not find in the literature any other case of penile sarcoma with such histological...

primary sarcomas of the kidney are exceptional. among renal sarcomas, leiomyosarcoma is the most common histologic subtype amounting to 50-60% of all cases. the tumor usually arises from either the renal capsule or smooth muscle tissue in the renal pelvic wall. in this paper, we report a patient with leiomyosarcoma of the kidney presented with non-specific abdominal pain and a palpable mass. hi...

Undifferentiated pleomorphic sarcoma is uncommonly seen and can be present in soft tissue as a slow-growing painless mass. The usual presenting symptoms of these tumors are swelling, pain, constitutional symptoms. However, an initial presentation embolic stroke rarely seen. We report patient who presented with cerebellar had widespread pulmonary nodules on chest X-ray. Computed Tomography (CT)-...

Abstract Objectives Programmed death ligand-1 (PD-L1) expression in malignant epithelial neoplasms has been the subject of numerous studies; however, less data on its application to sarcomas are available. This research focused PD-L1 and how it correlated with clinicopathological characteristics soft tissue sarcomas. Materials Methods The anti-PD-L1 antibody Ki-67 were stained 50 cases sarcoma ...

0.1%–0.2% of all malignant tumours and about 15% of all sarcomas. Liposarcoma is the most common type of retroperitoneal sarcoma (41%), followed by leiomyosarcoma, malignant fibrous histiocytoma, fibrosarcoma and other undifferentiated sarcomas. We report the case of a woman with a giant retroperitoneal sarcoma and show that large tumour size is not necessarily a contraindication to surgical ex...

BACKGROUND Distinguishing an atypical lipomatous tumor/well-differentiated liposarcoma from a benign lipomatous tumor on morphology alone can be difficult and there is an established role for MDM2 fluorescent in situ hybridization studies in making this differential diagnosis. There is no literature on the role for MDM2 fluorescent in situ hybridization studies in distinguishing between a well-...