Liver is the central metabolic organ that regulates body’s energy supply, secretes several essential compounds and clears substances by several methods, including recycling, inactivation andexcretion. Global loss of the liver function results in profound metabolic instability and disruption of essential functions such as acid-base balance and thermoregulation leading to acute liver failure (ALF...

Ventricular septal defects (VSDs) are estimated to account for 20 to 30% of all congenital heart defects (CHDs). Although a residual shunt is the most common complication of VSD surgery, a second operation that applies the surgical repair method is very difficult because it can increase the possibility of uncontrolled bleeding and the severity of tissue adhesion. Here, we present the first case...

Adenocarcinoma arising from adenomyosis uteri is rare. Herein, we reported a patient with papillary serous carcinoma arising from adenomyosis. The patient was a 61-year-old woman who received tamoxifen for treatment of her breast cancer over the past five years. In hysterectomy specimen taken for investigating her uncontrolled bleeding with suspicion of uterine myoma, multiple adenomyotic foci ...

Primary angiosarcoma of the spleen is an extremely rare malignant neoplasm of vascular origin that often has a poor prognosis. The majority of cases presents with splenic rupture and hemorrhage. The present study retrospectively analyzed the case of 77-year-old female who presented with diffuse abdominal pain and distension. During laparotomy, a huge actively bleeding spleen was identified and ...

Uncontrolled hemorrhage is the leading cause of preventable combat-related deaths. The vast majority of these deaths occur in the field before the injured can be transported to a treatment facility. Early control of hemorrhage remains the most effective strategy for treating combat casualties. A number of hemostatic agents have recently been deployed to the warfront that can be used to arrest b...

P a t i e n t s 2301 patients who were having primary total knee replacement and weighed between 40 and 136 kg. Exclusion criteria included pneumatic leg compression; immobilization ≥ 3 days; major surgery, stroke, myocardial infarction, or receipt of study drug ≤ 30 days before surgery; increased risk for bleeding ≤ 90 days before surgery; uncontrolled hypertension; thrombocytopenia; drug or a...

Background/Introduction The indications for urgent valve replacement in patients with infective endocarditis (IE) include uncontrolled infection, recurrent emboli, valve dysfunction and cardiac failure. The optimal timing of this surgery when IE is complicated by cerebrovascular events (such as cerebral infarction or haemorrhage) is controversial, largely due to the escalated risk of perioperat...

Thrombolysis, a standard therapy for ST elevation myocardial infarction (STEMI) in non-PCI-capable hospitals, may be catastrophic for patients with aortic dissection leading to further expansion, rupture and uncontrolled bleeding. Stanford type A aortic dissection, rarely may mimic myocardial infarction. We report a case of a patient with an inferior STEMI thrombolysed with tenecteplase and fol...