In this article, we use a measure of expected true evidence for determine the required sample size in type-II censored experiments for obtaining statistical evidence in favor of one hypothesis about the exponential mean against another.

The catalytic highly regio-, diastereo-, and enantioselective synthesis of a small library of spiropyrrolizidineoxindolesvia a four-component 1,3-dipolar cycloaddition reactionof azomethineylides, derived from isatin, with electron-deficient dipolarophilewas described. The process occurs at room temperature in aqueous ethanol as a green solvent and in the presence of a bidendatebis(imi...

Synthesis of enantiomerically pure isoxazolidine via an asymmetric 1,3- dipolar cycloaddition reaction of nitrone with electron-deficient dipolarophile was described. The process occurs at room temperature in aqueous ethanol as a green solvent and in the presence of a bidendate bis(imine)–Cu(II)triflate complex as catalyst. The reaction mechanism is discussed on the basis of the assignment of t...

The catalytic highly regio-, diastereo-, and enantioselective synthesis of a small library of spiropyrrolizidineoxindolesvia a four-component 1,3-dipolar cycloaddition reactionof azomethineylides, derived from isatin, with electron-deficient dipolarophilewas described. The process occurs at room temperature in aqueous ethanol as a green solvent and in the presence of a bidendatebis(imi...

We experimentally demonstrate that a type-II pulsed optical parametric amplifier operated in a phaseinsensitive configuration works as a near-perfect classical optical amplifier whose noise figure approaches 3 dB at high gains. We further demonstrate that, when operated in a phase-sensitive configuration, this amplifier works as a quantum-optical amplifier whose noise figure goes below 3 dB and...

Muscle afferent neurons that express transient receptor potential vanilloid type I (TRPV1) are responsible for muscle pain associated with tissue acidosis. We have previously found that TRPV1 of isolectin B4 (IB4)-negative muscle nociceptors plays an important role in the acid-induced hyperalgesic priming and the development of chronic hyperalgesia in a mouse model of fibromyalgia. To understan...

We demonstrate a polarization-entangled photon-pair source obtained via a type-II non-collinear quasi-phase-matched spontaneous parametric down-conversion process with a 10-mm periodically poled KTiOPO4 crystal, which is as stable and wavelength-tunable as the well-known Sagnac configuration scheme. A brightness of 4.2 kHz/mW is detected and a concurrence of 0.975 is estimated using quantum sta...

Implementing the use of solid electroactive materials in redox-flow battery (RFB) configuration is an appealing challenge since resulting technologies benefit from high energy density and independent scalability power RFB configuration. In recent years, two different strategies have emerged to achieve this goal: i) semi-solid flow batteries ii) redox-mediated batteries, also referred as redox t...

Background: Lead is one of the sustainable metals with devastating effects on many tissues. This study, examined the adverse effect of lead poisoning on the gene expression of collagen type II and osteocalcin by mesenchymal stem cells (MSCs) cultured in chondrogenic and osteogenic media, respectively. Methods: We used 18 male Wistar rats, divided in 3 groups. In addition to libitum feed as the...

The zirconium isotopes with $A=92--110$ have one of the most complicated evolution structure in nuclear chart. In order to understand structural these isotopes, we carry a detailed calculation definite symmetry-based framework, interacting boson model configuration mixing (IBM-CM). We compare our large range experimental data, such as energy levels, two-neutron separation energies, $E2$ and $E0...