INTRODUCTION One challenging problem in patients suffering from Diabetes Mellitus (DM) is the elevate incidence of cardiovascular events. Exercise has been proved useful in reducing cardiovascular risks in these patients. However, both type 1 and 2 DM significantly affect the cardiovascular response during exercise. Therefore, on one side exercise is considered to be a valid therapeutic tool fo...

Adipocyte fatty acid binding protein (A-FABP) is a key mediator of obesity-related metabolic syndrome (MetS). The aim of this study was to evaluate the relationship between A-FABP concentration and MetS in type 2 diabetes mellitus (DM) patients. Fasting blood samples were obtained from 165 type 2 DM volunteers. MetS and its components were defined using diagnostic criteria from the Internationa...

The current pandemic of type 2 diabetes mellitus (DM) is accelerating [1, 2] in a world where approximately one-third of the population is latently infected with Mycobacterium tuberculosis [3]. DM affects 230 million persons worldwide, and this number is anticipated to reach 366 million by 2030, at which time 80% of those affected will be living in low-and middle-income countries, where active ...

Inflammation, decreased levels of circulating endothelial nitric oxide (eNO) and brain-derived neurotrophic factor (BDNF), altered activity of hypothalamic neurotransmitters (including serotonin and vagal tone) and gut hormones, increased concentrations of free radicals, and imbalance in the levels of bioactive lipids and their pro- and anti-inflammatory metabolites have been suggested to play ...

AIMS To identify the threshold of reduced sensory perception in Type 2 diabetes mellitus (Type 2 DM) using a range of research grade monofilaments. METHODS Three groups of participants were recruited into a between subject, cross-sectional study. Group 1(NEW), persons with Type 2 DM diagnosed for less than 2 years (n = 80); Group 2 (EST) persons with Type 2 DM diagnosed for more than 2 years ...

OBJECTIVE The co-occurrence of autoimmune diseases such as rheumatoid arthritis (RA) and type 1 diabetes mellitus (DM) has been reported in individuals and families. In this study, the strength and nature of this association were investigated at the population level in a Swedish case-control cohort. METHODS For this case-control study, 1,419 patients with incident RA diagnosed between 1996 an...

Background Diabetes mellitus (DM) is a common comorbidity of Cushing’s syndrome (CS) and plays an important role in morbidity and death of patients with uncontrolled hypercortisolism. Some authors define DM in CS as a ‘specific type of diabetes secondary to endocrinopathy’, although others judge it as a classical form of type 2 DM. Glucocorticoid (GC) excess causes pancreatic beta cell dysfunct...

Objective: Correlation of osteoporosis (OP) with type 2diabetes mellitus (DM) , is not as clear as type 1 DM. The purpose of this study was to compare the frequency of OP and osteoporotic fractures in post- menopausal women with and without type 2 DM in Sari, Iran. Materials and Methods: Eighty post-menopausal women with type 2 DM and 80 non-diabetic controls enrolled in this study. Bone mine...