Abstract Background Aortic stenosis (AS) is the most common valvular disease in developed countries. Specific timing of intervention for asymptomatic patients with severe aortic and preserved ejection fraction remains controversial. Purpose To compare outcomes early valve replacement (AVR) versus watchful waiting (WW) AS ejection. Methods We systematically searched PubMed, Embase Cochrane datab...

BACKGROUND Bleach baths have been proposed as a treatment for decreasing the severity of atopic dermatitis (AD). However, conflicting results have been found regarding their efficacy. OBJECTIVE To determine the efficacy of bleach vs water baths at decreasing AD severity. METHODS We performed a systematic review of all studies evaluating the efficacy of bleach baths for AD. Cochrane, EMBASE,...

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) use for circulatory support in shock is limited by increased left ventricular afterload. Impella and intra-aortic balloon pump (IABP) can be used conjunction with VA-ECMO to help unload the ventricle. Data comparing two strategies are limited. Purpose We performed a systematic review meta-analysis of published data ...

A mathematical framework that permits the factorization of a joint probability distribution into its localized components for a two-dimensional array of pixels is presented. The factorization was used to estimate the contribution to mutual information of two- (I2) and three-pixel (I3) luminance correlations for a large ensemble of natural images analyzed at various spatial scales and pixel dept...

BACKGROUND Mycoplasma genitalium is a common cause of non-gonococcal non-chlamydial urethritis and cervicitis. Testing of asymptomatic populations has been proposed, but prevalence in asymptomatic populations is not well established. We aimed to estimate the prevalence of M. genitalium in the general population, pregnant women, men who have sex with men (MSM), commercial sex workers (CSWs) and ...

Oxidation of 3,4-ethylenedithio-3'-iodo-tetrathiafulvalene (EDT-TTF-I) and 3,4-ethylenedithio-3',4'-diiodo-tetrathiafulvalene (EDT-TTF-I2) with DDQ afforded two different salts formulated as (EDT-TTF-I)(DDQ) and (EDT-TTF-I2)2(DDQ)·(CH3CN), both characterized with a full charge transfer to the DDQ acceptor moiety and by short and linear halogen bonding interactions between the iodine atom as hal...

The photodissociation dynamics of I3- from 390 to 290 nm (3.18 to 4.28 eV) have been investigated using fast beam photofragment translational spectroscopy in which the products are detected and analyzed with coincidence imaging. At photon energies < or = 3.87 eV, two-body dissociation that generates I- + I2(A 3Pi1) and vibrationally excited I2- (X 2Sigmau+) + I(2P(3/2)) is observed, while at en...

BACKGROUND Pectus excavatum is the most common congenital chest wall deformity. The two most common surgical techniques for its correction are the modified Ravitch technique and the minimally invasive Nuss technique. Despite both procedures being used widely, data comparing them are scarce. METHODS We conducted a systematic review and meta-analysis of comparative studies to evaluate these pro...

Abstract Background Recently published randomized controlled trials (RCT) have questioned the utility of Fraction Flow Reserve (FFR) to guide revascularization in patients with multivessel coronary artery disease (CAD) as compared Angiography Purpose This current analysis aimed compare clinical outcomes associated FFR guided versus standard angiography-guided for CAD using a large number stable...