CONTEXT High-grade T1 (formerly T1G3) bladder cancer (BCa) has a high propensity to recur and progress. As a result, decisions pertaining to its treatment are difficult. Treatment with bacillus Calmette-Guérin (BCG) risks progression and metastases but may preserve the bladder. Cystectomy may offer the best opportunity for cure but is associated with morbidity and a risk of mortality, and it ma...

OBJECTIVES The objective of this study was to compare the recurrence rate and de novo incontinence after endoscopic treatment of vesicourethral stenosis (VUS) after radical prostatectomy (RP) and for bladder neck stenosis (BNS) after transurethral resection of the prostate (TURP). METHODS Retrospective analysis of patients treated endoscopically for VUS after RP or for BNS after TURP at three...

Sarcomatoid carcinoma of the prostate is among the rarest malignant neoplasm types and has been well known for its aggressive clinical course. Patient was admitted with the symptoms of lower urinary tract. Transurethral resection of prostate (TUR-P) was carried out. Revealing Gleason 5 + 3 = 8 prostate adenocarcinoma in TUR-P material. Thereby, a Radical Prostatectomy procedure was planned. In ...

AIM To evaluate the impact of early re-resection on the incidence of tumour recurrence and progression in patients with pT1 high-grade non-muscle invasive bladder cancer (HG-NMIBC). PATIENTS AND METHODS From 2001 to 2008, 486 consecutive patients were diagnosed with pT1 HG-NMIBC. Data were collected retrospectively which included patient demographics, histological parameters including the pre...

BACKGROUND The effect of intravesical instillation of doxorubicin or epirubicin after transurethral resection (TUR) was estimated from the data of five randomized clinical trials in Japan. The authors provided the estimated hazard function plots with a smoothing technique, to evaluate the prophylactic effect of an intravesical therapy over time and to estimate the natural history of superficial...

Introduction Vaccine manufacturers evaluate the efficiency of their vaccine according to the method which is defined in the European Pharmacopoeia. Regarding foot-and-mouth disease (FMD) vaccine there are some difficulties to find animals for potency tests in the countries like Turkey where FMD is endemic and vaccine campaigns are carried out. In addition, potency tests must be carried out in c...

No. Biomarker Description and Findings Type Potential Use 389 Gamma-H2AX Highly sensitive marker for DNA double-stranded breaks after ionizing radiation Peripheral blood lymphocytes BC risk 390 Ki-67 High Ki-67 index increases probability of high grade Ta and T1 BC recurrence Tissue Recurrence risk 393 Unexplained leukocytosis Unexplained leukocytosis of greater than 20 × 103 cells/μl correlate...