نتایج جستجو برای: tumour necrosis factor

تعداد نتایج: 931879  

2015
David L Scott Fowzia Ibrahim Vern Farewell Aidan G O’Keeffe David Walker Clive Kelly Fraser Birrell Kuntal Chakravarty Peter Maddison Margaret Heslin Anita Patel Gabrielle H Kingsley

OBJECTIVE To determine whether intensive combinations of synthetic disease modifying drugs can achieve similar clinical benefits at lower costs to high cost biologics such as tumour necrosis factor inhibitors in patients with active rheumatoid arthritis resistant to initial methotrexate and other synthetic disease modifying drugs. DESIGN Open label pragmatic randomised multicentre two arm non...

Journal: :The European respiratory journal 1996
H Nakamura T Hino S Kato Y Shibata H Takahashi H Tomoike

This study aimed to investigate the expression of tumour necrosis factor receptor (TNF-R) at the gene and surface level, and its shedding in human lung tissue and a pulmonary epithelial cell line, A549. Levels of gene expression of TNF-R were evaluated by Northern blot analysis. Human lung tissue expressed both type I and type II TNF-R gene, while A549 cells expressed only type I TNF-R gene. Ph...

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