As breast cancer screening rates increase, smaller and more numerous lesions are being identified earlier, leading to more breast-conserving surgical procedures. Achieving a clean surgical margin represents a technical challenge with important clinical implications. Optical coherence tomography (OCT) is introduced as an intraoperative high-resolution imaging technique that assesses surgical bre...

Malignant tumor originated from external auditory canal (EAC) is very rare with an annual incidence of around 1 per million. Pathologically, squamous cell carcinoma is incidentally most common, and adenoid cystic carcinoma, basal cell carcinoma, and melanoma follow in decreasing order. Due to the rarity of malignant tumor of EAC, there is no widely accepted treatment modality yet. But basal cel...

Tumor surgical resection margin status is important for any malignant lesion. When this occurs in conjunction with efforts to preserve or conserve the afflicted organ, these margins become extremely important. With the demonstration of no difference in overall survival between mastectomy versus lumpectomy and radiation for breast carcinoma, there is a definite trend toward smaller resections co...

Linear basal cell carcinoma (BCC), which has a ratio of its long and short axes of more than 3: 1, is a distinct clinical entity among BCC. We report the first case report of a linear BCC in an Asian patient. An 87 year-old woman presented with an ulcerated black nodule, 15x5mm (3: 1), on her nasojungal fold of the right lower eyelid. The tumor was excised with 5 mm safety margin. The pathologi...

OBJECTIVE The authors determined whether microscopically positive surgical margins are detrimental to the outcome of early stage breast cancer patients treated with conservation surgery and radiation therapy. SUMMARY BACKGROUND DATA The optimal extent of breast surgery required for patients treated with conservation surgery and radiation therapy has not been established. To achieve breast pre...

Objective: Breast-conserving surgery (BCS) experienced a significant surge during the last decades due to increase of early breast cancer detection. Central discussion is margin adequacy which represents one most predictive factors for local relapse. This paper aims shed light on problem margins in surgery. Mechanism: We performed systematic narrative review literature by conducting search usin...

Positive margins have been a critical issue that hinders the success of breast- conserving surgery. The incidence of positive margins is estimated to range from 20% to as high as 60%. Currently, there is no effective intraoperative method for margin assessment. It would be desirable if there is a rapid and reliable breast cancer margin assessment tool in the operating room so that further surge...

BACKGROUND Defects caused by excision of benign lid margin tumors are conventionally repaired by reconstructive surgery. However, second intention healing is another option for managing wounds on the lid margin. OBJECTIVE To evaluate the effectiveness of second intention healing after a shave excision of benign tumors on the lid margin. METHODS Lid defects following a shave excision of the ...

The localized cutaneous amyloidosis occurring on the upper lip of a 48-year-old man was surgically treated and aesthetically reconstructed with vermilion submucosal pedicle partial-thickness cross-lip flap. The reconstruction of the upper lip following the tumor resection or trauma with Abbe flap or its modified methods may not be always satisfactory because it leaves parallel scars extending t...