نتایج جستجو برای: tumor associated antigen

تعداد نتایج: 1998750  

Journal: :Journal for ImmunoTherapy of Cancer 2021

Background T cells play a central role in tumor immunity. In principle, cell requires antigen recognition by T-cell receptor (TCR) to gain effector function. Antigen-driven activation leads clonal expansion with generation of progeny that all express the same chronotypic TCR. This makes TCR analysis useful tool comprehensively and individually understand antigen-specific responses. Indeed, we p...

Journal: :European journal of medical and health sciences 2022

Breast cancer remains one of the most frequent malignancies in women and primary cause cancer-related death all over world. Hormones tumor biomarkers have been implicated as possible causes prognostic breast cancer. The present study investigated use serum hormonal levels biomarkers; Carcinoembrvonic antigen (CEA), (CA 15-3) for diagnosis Cancer, generation different subtypes using Estrogen rec...

Journal: :Cancer research 1984
M Abe D W Kufe

We have monitored the effects of sodium butyrate on expression of a human breast tumor-associated antigen defined by a murine monoclonal antibody designated DF3. This cell surface antigen has a molecular weight of approximately 300,000 and is related to a higher-molecular-weight antigen detectable in human milk. The results demonstrate that butyrate increases the membrane expression of the DF3 ...

Journal: :journal of biotechnology and health sciences 0
ali-akbar zare department of biotechnology, school of allied medicine, qazvin university of medical sciences, qazvin, ir iran; cancer genetics department, breast cancer research center, acecr, tehran, ir iran keivan majidzadeh-a cancer genetics department, breast cancer research center, acecr, tehran, ir iran; tasnim biotechnology research center (tbrc), school of medicine, aja university of medical sciences, tehran, ir iran rezvan esmaeili cancer genetics department, breast cancer research center, acecr, tehran, ir iran nematollah gheibi cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran mohammad reza sarookhani department of biotechnology, cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran; department of biotechnology, cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran. tel: +98-9121823059, fax: +98-2833345862

conclusions expression of armc3 in tumor samples and normal adjacent tissue is very important. the expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. accordingly, aberrant expression of armc3 in tumor samples may be an attractive candidate for use as a tumor ...

Journal: :Cancer immunology research 2017
Tullia C Bruno Peggy J Ebner Brandon L Moore Olivia G Squalls Katherine A Waugh Evgeniy B Eruslanov Sunil Singhal John D Mitchell Wilbur A Franklin Daniel T Merrick Martin D McCarter Brent E Palmer Jeffrey A Kern Jill E Slansky

Effective immunotherapy options for patients with non-small cell lung cancer (NSCLC) are becoming increasingly available. The immunotherapy focus has been on tumor-infiltrating T cells (TILs); however, tumor-infiltrating B cells (TIL-Bs) have also been reported to correlate with NSCLC patient survival. The function of TIL-Bs in human cancer has been understudied, with little focus on their role...

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