tuberculosis is an infection which may influence many organs while ocular tuberculosis (tb) is amongst the rarest infectious diseases with no sign of systemic disease. a fifty-six-year- old female with complaint of gradual loss of visual acuity, weight loss, night sweats and purulent discharge from medial canthus and non-productive coughs. in general, tuberculosis in endemic areas, even the rar...

splenic tuberculosis is a rare entity, particularly among immunocompetent hosts. hererin, we present a 23 year-old man who was reffered with fever of unknown origin and eventually diagnosed to have splenic tuberculosis with an involvement of a single axillary lymph node as the sole site disease in the other organs.despite two months of treatment with antituberculous agents due to necrotising gr...

Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features. We evaluated the use of in situ polymerase chain reaction (PCR) using Mycobacterium tuberculosis complex-specific primers for IS 6110 to differentiate these 2 disorders in archival mucosal biopsy specimens. In situ PCR was positive in 6 of 20 tu...

background: tuberculosis (tb) is a major cause of death worldwide. finding an effective vaccine against tb is the best way to control it. several vaccines against this disease have been developed but none are completely protective. the aim of this study was to design and construct a cloning vector containing the mycobacterium tuberculosis (m. tuberculosis) heat shock protein x (hspx). methods: ...

Background: Cutaneous tuberculosis (TB) is a chronic infectious disease affecting the skin caused by Mycobacterium (M. tuberculosis). It constitutes 1–1.5% of extrapulmonary TB, with Indonesia being third-highest TB burden country worldwide. difficult to diagnose due its varied presentations. This study aimed describe clinicodemographic and laboratory characteristics cutaneous in tertiary refer...

Background Low and deficient levels of vitamin A are common in low- and middle-income countries where tuberculosis burden is high. We assessed the impact of baseline levels of vitamin A and carotenoids on tuberculosis disease risk. Methods We conducted a case-control study nested within a longitudinal cohort of household contacts (HHCs) of pulmonary tuberculosis case patients in Lima, Peru. W...

Tuberculosis (TB) is the commonest cause of infection-related death globally. Disseminated tuberculosis a life-threatening disease which results from hematogenous spread Mycobacterium tuberculosis. Genitourinary (GUTB) usually caused as result mycobacteria during initial infection. The patient's clinical presentation may vary asymptomatic to non-specific symptoms related organ involved and also...