BACKGROUND Although the association of clinical hypothyroidism with cognitive deficits is well known, the cognitive effects of thyroid hormones in euthyroid subjects are less studied and understood. The purpose of this study was to examine thyroid-cognition relationships in healthy, euthyroid older men. METHODS We examined healthy men (N = 44, mean age = 72), excluding clinically hypothyroid/...

BACKGROUND Rotational alignment of the tibial component is important for long-term success of total knee arthroplasty (TKA). This study aimed to compare five axes in normal and osteoarthritic (OA) knees to determine a reliable landmark for tibial rotational alignment in TKA. METHODS One hundred twenty patients with OA knees and 40 with normal knees were included. The angle between a line perp...

The lack of reliable outcome predictors and the delayed onset of therapeutic response to antidepressants are among the clinical challenges in the treatment of depression. Identifying clinical correlates associated with antidepressant response would reduce symptom severity and morbidity for patients with depression. Twenty-three subjects with major depression were treated with citalopram 20 mg/d...

In this study, the effect of coenzyme Q10 (CoQ10) on nitric oxide (NO) and total antioxidant (TAS) capacity in rats for which experimentally hypothyroidism was induced through PTU investigated. A 32 healthy male Wistar Albino weighing 300-350g, approximately 12 weeks old, were used as animal material study. . Rats divided into 4 experimental groups control (K), Coenzyme (C), Hypothyroidism (H),...

In view of their perceived chemopreventive activities against hormone-dependent cancers, cardiovascular disease, and postmenopausal ailments, there is considerable interest in engineering plants to contain isoflavone phytoestrogens. However, attempts to date have only resulted in low levels of isoflavone accumulation in non-legumes. Introducing soybean isoflavone synthase (IFS) into Arabidopsis...

OBJECTIVE: To find out the Tetanus Toxoid (TT) vaccination coverage in the pregnant women and to assess the factors likely to be associated with TT vaccination coverage in women of reproductive age. SUBJECTS AND METHODS: A cross sectional survey was conducted in the Obstetrics and Gynecology out Patient Department (OPD) of Isra University for the period of three months from March 2008 to June 2...

The purpose of this study was to evaluate the reliability of a 1-km cycling time trial using a Wattbike cycling ergometer in competitive cyclists. Ten competitive male cyclists (mean ± SD; 63.9 ± 5.1 mL•kg -1 •min -1 ) performed a VO2max test and a familiarization of the 1-km time trial (TT) on the same day, and 3 separate 1-km TT (TT1, TT2 and TT3) separated by >24 hours. Mean performance time...

Background. The present study is to look for a correlation between oxidative stress and thyroid function in patients with the nephrotic syndrome in the remission phase as well as in a persistent proteinuric state. Introduction. Nephrotic syndrome is a form of chronic kidney disease due to which blood loses protein through the urine. We wanted to know if there was an increased loss of thyroid ho...

To investigate the effect of hypothyroidism on gonadal and adrenal functions in male Japanese quail (Coturnix japonica), hypothyroidism was induced in male adult Japanese quail by daily administration of 2-Mercapto-1-methylimidazole (methimazole) in their drinking water. Four weeks after methimazole treatment, the Japanese quail were sacrificed, and the plasma concentrations of free triiodothyr...

The aim of the study was to determine whether thyroid hormones level on admission in patients with ischemic stroke, treated with intravenous recombinant tissue type plasminogen activator (rtPA), was associated with symptomatic intracranial hemorrhage (sICH) and worse outcomes at 3 months.Patients with acute ischemic stroke (AIS) receiving intravenous rtPA thrombolytic treatment on our stroke un...