The Akaike (1973, 1974) information criterion, AIC, and the corrected Akaike information criterion (Hurvich and Tsai, 1989), AICc, were both designed as estimators of the expected Kullback-Leibler discrepancy between the model generating the data and a tted candidate model. AIC is justiied in a very general framework, and as a result, ooers a crude estimator of the expected discrepancy: one whi...

In this article, a semi-analytical solution is provided to investigate the free vibration characteristics of rotating truncated conical shells surrounded by Winkler–Pasternak type foundation. It assumed that material shell composed epoxy as matrix and graphene nanoplatelets (GPLs) reinforcement dispersed in both thickness length directions shell. The modeled based on first-order shear deformati...

Da Costa, Ines; Belnou, Pierre; Soulier, Anne; Lapidus, Nathanael; Tsai, Eileen S.; Bourcier, Elsa; Moisi, Laura; Sautet, Alain; Bonnet, Francis; Lescot, Thomas; Verdonk, FranckAuthor Information

The COUP (chicken ovalbumin upstream promoter) transcription factor binds to the upstream promoters of both the chicken ovalbumin and the rat insulin II genes, even though the two binding sites have no obvious sequence similarity (Hwung, Y.-P., Crowe, D. T., Wang, L.-H., Tsai, S. Y., and Tsai, M.-J. (1988) Mol. Cell. Biol. 8, 2070-2077). Comparison of the contact points and important nucleotide...

The unsprung masses associated with the axles of a railway vehicle result in costly impact damage to rail infrastructure. A hybrid metallic-composite (HMC) axle is evaluated using finite element analysis. mass 74 kg, 63% lighter than an equivalent hollow steel axle. HMC comprises full length, carbon fibre reinforced, epoxy matrix composite tube secondary overwrapping for stiffness and EA1N grad...

Many algorithms for the modelling and calculation of the dynamics of rigid parallel manipulators already exist, and are based on two approaches: The Newton-Euler method and the Lagrangian principle. For the Newton-Euler method the dynamics equations are generated by the complete analysis of all forces and torques of each rigid body in the robot’s structure (Featherstone & Orin, 2000, Spong & Vi...

The manuscript by Tsai et al. (935-945) is a tour de force analysis of a controversial issue in developmental neurobiology, namely the molecular basis of the devastating human brain malformation, type I lissencephaly (Lis1) (Jellinger, K., and A. Rett. 1976. Neuropadiatrie. 7:66-91). For several decades, defects in neuronal migration have been assumed to underlie all defects in cortical histoge...