Background Monoclonal antibodies (Mabs) have been recently used for the treatment of virtually every debilitating disease. Packed-bed bioreactors have been used for the cultivation and production of a wide range of cell lines and biologics including MAbs. The principle behind a Packed-bed bioreactor is that the cells are being immobilized within a suitable stationary matrix which is represented...

Efficient transport of regulatory molecules is one of the main requirements for directing the growth and differentiation of bone marrow stromal cells (BMSC). We have designed and utilized a packed bed bioreactor system for cultivation of murine BMSC immobilized in alginate microbeads produced by electrostatic droplet generation. Continuous medium perfusion at velocities that are physiological f...

The IPv6 Routing Protocol for Low Power and Lossy networks (RPL) is a routing protocol standardized by the Internet Engineering Task Force. According to specification of protocol, Trickle algorithm adopted dissemination route construction information among nodes in such networks. Since originally designed code propagation maintenance Wireless Sensor Networks, when using formation network there ...

Abstract Power-to-methane technology is a promising solution to facilitate the use of excess variable renewable energy for biomethane production. In this approach, hydrogen produced via electrolysis used upgrade raw biogas, which can be subsequently as fuel or stored in gas grid. Ex-situ biomethanation an emerging that could potentially replace conventional energy-intensive biogas upgrading met...