BACKGROUND Adherence to Antiretroviral Therapy (ART) is critical piece in the management of HIV infected patients. Despite the benefits of ART, non-adherence to ART persists. This study explores association between patient's knowledge of the ART line of treatment, availability of future treatment options and adherence. METHODS A cross sectional survey of HIV infected adolescent and adults was...

BACKGROUND: Adherence to anti-hypertensive treatment is essential for effective control of hypertension. Problem with follow-up of therapeutic recommendations is common in hypertension, and this highly impacts the effectiveness of treatment. Poor adherence to treatment would be responsible for two-thirds of uncontrolled hypertension. Objectives: The present study had the objectives of assessing...

The effectiveness of disease-modifying drugs in the treatment of multiple sclerosis is associated with adherence. RebiSmart® electronic device provides useful information about adherence to the treatment with subcutaneous (sc) interferon (IFN) β-1a (Rebif®). The aim of the study was to determine long-term adherence to this treatment in patients with relapsing-remitting multiple sclerosis (RRMS)...

introduction: tyrosine kinase inhibitors (tkis) were the first drugs to use an intracellular signaling molecule as a therapeutic target. unresponsiveness to tkis limits therapeutic options, making allogeneic hematopoietic stem cell transplantation (hsct) the only option leading to molecular remission. objectives: to characterize cml patients unresponsive to first- and/or second-generation tki t...

Abstract Introduction: Diabetes is a chronic disease with fatal health complications. Identifying the psychological factors that control this disease is very important, one of which is quality of life (QOL). Objective: This study aimed to investigate the effect of a QOL education program on psychological well-being (PWB) and adherence to treatment of patients with type 2 diabetes. Materials ...

The purpose of this paper was to systematically review the literature related to research about the factors affecting treatment adherence and discontinuation of atomoxetine in pediatric, adolescent, and adult patients with attention-deficit/hyperactivity disorder (ADHD). Medline was systematically searched using the following prespecified terms: "ADHD", "Adherence", "Compliance", "Discontinuati...

Purpose: To study the adherence to clinical treatment in patients with Juvenile Myoclonic Epilepsy (JME) and its correlation to Quality of Life (QOL) scores, and antiepileptic drugs (AEDs) adverse effects. Methods: Fortythree JME (ILAE,1989) outpatients in regular treatment were evaluated by clinical anamnesis and EEG/videoEEG at Hospital São Paulo, UNIFESP, Brazil. They answered a self-report ...