441–445. 13. Walichiewicz P, Przybyszewski WM, Snietura M, Lange D, Bkhiyan A, Widel M. Protective effect of local temporary ischemia depends on applied dose of radiation. Cancer Lett 2005;222:113–118. 14. Thielmann M, Kottenberg E, Kleinbongard P, Wendt D, Gedik N, Pasa S, Price V, Tsangakis K, Neuhäuser M, Peters J, Jakob H, Heusch G. Cardioprotective and prognostic effects of remote ischaemi...

The multimeric membrane-tethering complexes TRAPPI and TRAPPII share seven subunits, of which four (Bet3p, Bet5p, Trs23p, and Trs31p) are minimally needed to activate the Rab GTPase Ypt1p in an event preceding membrane fusion. Here, we present the structure of a heteropentameric TRAPPI assembly complexed with Ypt1p. We propose that TRAPPI facilitates nucleotide exchange primarily by stabilizing...

The formula (1) was first used by Schur [22], but the idea of the Schur complement goes back to Sylvester (1851), and the term Schur complement was introduced by E. Haynsworth [16]. In the beginning Schur complements were used in the theory of matrices. M.G. Krein [19] and W.N. Anderson and G.E. Trapp [4] extended the notion of Schur complements of matrices to shorted operators in Hilbert space...

A13-year-old boy with no significant past medical history was admitted to our institution with pharyngitis, oral ulcers, and dehydration. He was well until 8 days prior to admission when he developed a fever to 103o F and pharyngitis. He was seen by his primary care physician, who ordered a rapid strep test and throat culture, both of which were negative, so symptomatic care was recommended. Fo...