OBJECTIVE To evaluate tumor control with plaque radiotherapy for juxtapapillary choroidal melanoma that overhangs the optic disc. METHODS Retrospective medical record review of 141 consecutive patients with data on complications of treatment, final visual acuity, visual loss, enucleation, tumor recurrence, metastasis, and death. RESULTS The median patient age was 61 years. Presenting sympto...

E-mail: [email protected] Background: The evolution of ocular oncology over the recent decades has been characterized by the emphasis on organ saving approaches, the main method requirement being the greatest degree of radicalism of tumor resection with a minimum amount of damage to surrounding tissues. Purpose: To assess the efficacy of endoresection for uveal melanoma, with the high-frequency e...

CHOROIDAL NEVUS Choroidal nevus (Figure 1), the most common primary intraocular tumor,1 is a benign tumor that arises from melanocytic cells derived from the neural crest. Choroidal nevi are more common in white people, with 4% of the population having at least one.1 Malignant transformation into melanoma is possible; therefore, choroidal nevi should be monitored even though the rate is 1 in 4,...

Purpose: W e evaluated the impact of lower energy transurethral microwave thermotherapy on quality of life and quality of sexual function in patients w ith benign prostatic hyperplasia (B PH ). M aterials and Methods: A total of 50 patients with BPH were randomized to receive either lower energy transurethral microwave thermotherapy treatment (Prostasoft 2.0)* or placebo treatment and followed ...

PURPOSE Various autosomal recessive retinal dystrophies are reported to be associated with mutations in nuclear receptor subfamily 2, group E, member 3 (NR2E3, also called PNR) gene. The present study proposed to understand the clinical and genetic characteristics of the family of a patient with an ocular phenotype consistent with Goldmann-Favre syndrome (GFS) and vasoproliferative tumors of th...

BACKGROUND The management of retinoblastoma remains a challenge to the multidisciplinary team, particularly as treatment affects not only visual outcomes, but also ocular retention and morbidity. Management of retinoblastoma has evolved over the past two decades. OBJECTIVES To report the result of intra-ophthalmic artery chemotherapy (IAC) for the treatment of refractory and advanced retinobl...

BACKGROUND The aim of this study was to compare the efficacy of verteporfin photodynamic therapy (PDT), intravitreal injections of bevacizumab (IVB) and transpupillary thermotherapy (TTT) in patients with neovascular age-related macular degeneration (AMD). MATERIAL/METHODS The study design was a prospective, interventional, comparative case series. Between December 2006 and March 2009, 426 ey...

PURPOSE The purpose of this study was to report clinical outcomes of ruthenium-106 (106Ru) brachytherapy with or without additional local therapy for choroidal melanomas in Korean patients. MATERIALS AND METHODS A total of 88 patients diagnosed with choroidal melanomas were treated with 106Ru brachytherapy between 2006 and 2012. Patients were divided into two groups according to their tumor h...

OBJECTIVE To explore the clinical efficacy and prognostic factors of chemoreduction combined with topical treatment of advanced intraocular retinoblastoma (RB). MATERIALS AND METHODS A total of 22 eyes from 17 children with RB were selected for the study and treated with chemoreduction combined with topical cryotherapy, transpupillary thermotherapy (TTT) or episcleral plaque brachytherapy. Cl...