نتایج جستجو برای: translocation ability
تعداد نتایج: 462229 فیلتر نتایج به سال:
Light causes massive translocation of G-protein transducin from the light-sensitive outer segment compartment of the rod photoreceptor cell. Remarkably, significant translocation is observed only when the light intensity exceeds a critical threshold level. We addressed the nature of this threshold using a series of mutant mice and found that the threshold can be shifted to either a lower or hig...
Expression of the 5-HT(1Apl(a)) receptor in Aplysia pleural sensory neurons inhibited 5-HT-mediated translocation of the novel PKC Apl II in sensory neurons and prevented PKC-dependent synaptic facilitation at sensory to motoneuron synapses (Nagakura et al. 2010). We now demonstrate that the ability of inhibitory receptors to block PKC activation is a general feature of inhibitory receptors and...
Autotransporters (ATs) are a family of bacterial proteins containing a C-terminal β-barrel-forming domain that facilitates the translocation of N-terminal passenger domain whose functions range from adhesion to proteolysis. Genetic replacement of the native passenger domain with heterologous proteins is an attractive strategy not only for applications such as biocatalysis, live-cell vaccines, a...
rapid expansion of the industrial sector adds more effluent into the agricultural land and in the vicinity of industry, which possesses the major threat of land contamination and environmental degradation. the present study was conducted to determine toxic metal concentration in fly ash and metal accumulation potential of the saccharum munja and cynodon dactylon, the two main grass species grow...
one of the major causes of spontaneous abortion before the fourth month of pregnancy is chromosomal abnormalities. we report an unusual case of a familial balanced chromosomal translocation in a consanguineous couple who experienced 4 spontaneous abortions. chromosomal studies were performed on the basis of g-banding technique at high resolution and revealed 46, xx, t (16 6) (p12 q26) and 46, x...
Despite many advances in the treatment of breast cancer, it remains one of the leading causes of death among women. One hurdle for effective therapy is the treatment of the highly invasive and tumorigenic subpopulation of tumors called cancer stem cells (CSCs). CSCs, when stimulated with EGF, migrate through a physiological 3D collagen matrix at a higher velocity than non-stem cancer cells (non...
Mesenchymal stem cells (MSCs) are endowed with the unique capacity to raise an adaptive response environmental cues. This allows MSCs control their direct neighbourhood and endogenous tissue niche. Upon exposure of infection mimicking lipopolysaccharide (LPS), completely shift transcriptome release neutrophil activating chemokines. The LPS induced transcriptomic resulted in a significant increa...
the short arm of rye (secale cereale l.) chromosome 1 (1rs), besides being part of the rye genome, is present in many hundred wheat cultivars as either 1rs.1bl or 1rs.1dl wheat-rye translocation. in this study, the distribution of the wheat–rye translocation was examined in 33 iranian winter and spring wheat cultivars, nine of which had a known donor of 1rs.1bl translocation and the other 24 we...
chromosomal defects are relatively frequent in infertile men however, translocations between the y chromosome and autosomes are rare and less than 40 cases of y-autosome translocation have been reported. in particular, only three individuals has been described with a y;21 translocation, up to now. we report on an additional case of an infertile man in whom a y;21 translocation was associated wi...
The interaction of high density lipoproteins (HDL) with the HDL receptor stimulates the translocation of cholesterol from intracellular pools to the plasma membrane where the cholesterol becomes available for removal by appropriate acceptors. The role of signal transduction through protein kinase C in HDL receptor-dependent cholesterol translocation and efflux was examined using cholesterol-loa...
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