OBJECTIVE To compare the benefit and harm of restrictive versus liberal transfusion strategies to guide red blood cell transfusions. DESIGN Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. DATA SOURCES Cochrane central register of controlled trials, SilverPlatter Medline (1950 to date), SilverPlatter Embase (1980 to date), and Science Citatio...

a survey of tissue oxygenation differences in intensive care patients with blood transfusion     haghighimoghadamy [1] *, valizadeh ma [2] , feizi a [3]     received: 26 dec, 2011 accepted: 7 mar, 2012     abstract   background & aims : greater than 75% patient that hospitalized in intensive care units has anemia. blood transfusion in icu is not recently and about 40-70% patients in intensive c...

The relevance of this paper is that transfusion allogeneic blood to recipient animals always associated with immunological risks. In regard, the purpose study was assess state phagocytic activity neutrophils by indicators index, number, and oxygen-dependent bactericidal activity, as well establish changes in antibody-dependent cytotoxic lymphocytes rabbits during whole transfusion. Modelling tr...

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introduction: the main purpose of donor selection is not only the donor protection from blood donation complications but also the blood recipient not be expose to blood- transmitted diseases. this study aimed to determine the reason for exemption from donors among blood donor's who refer to ilam blood transfusion organization. materials and methods: this is a retrospective and descriptive ...

Blood transfusion has a well-documented clinical significance in several medical scenarios for instance severe anemia, massive blood loss caused by trauma, and major surgeries. Nevertheless, been associated with post-transfusion complications, such as mismatch reactions, transfusion-transmitted infections (TTIs).

abstract background beta-thalassemia is a common hereditary hemoglobinopathy, which is a reason of microcytic hypochromic anemia. patients with major thalassemia require multiple blood transfusions. this study evaluated growth in thalassemic patient and relationship with ferritin level. materials and methods this is a cross sectional study on seventy patients (36 boys, 34girls) with transfusion...

BACKGROUND Emergency or urgent surgery, which can be defined as surgery which must be done promptly to save life, limb, or functional capacity, is associated with a high risk of bleeding and death. Antifibrinolytic agents, such as tranexamic acid, inhibit blood clot breakdown (fibrinolysis) and can reduce perioperative bleeding. Tranexamic acid has been shown to reduce the need for a blood tran...

INTRODUCTION The understanding of coagulopathies in trauma has increased interest in thromboelastography (TEG®) and thromboelastometry (ROTEM®), which promptly evaluate the entire clotting process and may guide blood product therapy. Our objective was to review the evidence for their role in diagnosing early coagulopathies, guiding blood transfusion, and reducing mortality in injured patients. ...