Avoidance behavior constitutes a major transdiagnostic symptom that exacerbates anxiety. It hampers fear extinction and predicts poor therapy-outcome. Pavlovian counterconditioning with reward could alleviate avoidance better than traditional by reducing negative valence of the feared situation. However, previous studies are scarce did not consider pathological is often costly typically evolves...

Background: Approximately half of all asylum seekers suffer from trauma-related disorders requiring treatment, among them Posttraumatic Stress Disorder (PTSD), depression, anxiety, and somatic symptoms. There is a lack of easily accessible, low-threshold treatments taking the cultural background into account. Culturally Adapted CBT (CA CBT) is a well evaluated, transdiagnostic group interventio...

BACKGROUND Advancing research on the etiology, prevention, and treatment of psychopathology requires the field to move beyond modular conceptualizations of neural dysfunction toward understanding disturbance in key brain networks. Although some studies of anxiety and depression have begun doing so, they typically suffer from several drawbacks, including: (1) a categorical approach ignoring tran...

Mood instability is common, and an important feature of several psychiatric disorders. We discuss the definition and measurement of mood instability, and review its prevalence, characteristics, neurobiological correlates and clinical implications. We suggest that mood instability has underappreciated transdiagnostic potential as an investigational and therapeutic target.

Book details Riccardo Dalle Grave, Jason Aronson, The Rowman and Littlefield Publishing Group Inc., Maryland, 2013, vii + 341 pp., ISBN: 978-0-7657-0927-1. In the last 10 years, a new form of cognitive behavioural therapy for eating disorders, called Enhanced Cognitive Behavior Therapy (CBT-E) has been developed and tested by Christopher Fairburn and his colleagues at Oxford University. CBT-E d...