نتایج جستجو برای: tranilast

تعداد نتایج: 299  

Journal: :African Journal of Pharmacy and Pharmacology 2011

2016
Ichiro Kurokawa

Nodulocystic acne (NCA) usually develops subcutaneous epidermal cyst, granuloma, subcutaneous abscess, hypertrophic scar, keloids, and draining sinus. The pathogenesis of NCA is still unclear. Similar to NCA, acne conglobata (AC) is found in men predominantly with oily skin [1]. Lesions of AC begin in early puberty and culminate in late adolescent [1]. AC is one of the most therapy-resistant di...

Journal: :International journal of pharmaceutics 2015
Saad Tayyab Mohammed S Zaroog Shevin R Feroz Saharuddin B Mohamad Sri Nurestri A Malek

The interaction of tranilast (TRN), an antiallergic drug with the main drug transporter in human circulation, human serum albumin (HSA) was studied using isothermal titration calorimetry (ITC), fluorescence spectroscopy and in silico docking methods. ITC data revealed the binding constant and stoichiometry of binding as (3.21 ± 0.23) × 10(6)M(-1) and 0.80 ± 0.08, respectively, at 25°C. The valu...

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