Background: Osteoporosis one of the postmenopausal symptoms is characterized by bone loss. There is a link between excessive reactive oxygen species (ROS) formation, estrogen deficiency due to cessation of ovarian function and bone loss. Free radicals are responsible for causing osteoblast apoptosis and reducing osteoblastogenesis in bone remodeling. Vitamin E is a potent antioxidant with the a...

Most analyses of trabecular microarchitecture in mammals have focused on the functional significance of interspecific variation, but they have not effectively considered the influence of body size or phylogeny on bone architecture. The goals of this study were to determine the relationship between trabecular bone and body size in the humeral and femoral heads of extant primates, and to assess t...

A computational simulation method for three-dimensional trabecular surface remodeling was proposed, using voxel finite element models of cancellous bone, and was applied to the experimental data. In the simulation, the trabecular microstructure was modeled based on digital images, and its morphological changes due to surface movement at the trabecular level were directly expressed by removing/a...

Bone loss occurs during adulthood in both women and men and affects trabecular bone more than cortical bone. The mechanism responsible for trabecular bone loss during adulthood remains unexplained, but may be due at least in part to a reduced mechanoresponsiveness. We hypothesized that trabecular and cortical bone would respond anabolically to loading and that the bone response to mechanical lo...

Background. Bone diseases such as osteoporosis lead to changes in the trabecular bone mass and architecture. Improved methods for the quantitative assessment of trabecular bone are needed to better understand the role of trabecular architecture in bone strength. MR microscopy (MRM), with its ability to achieve resolutions below 50 μm, has proved to be particularly useful for the ex vivo evaluat...

orthodontic miniscrews are widely used as temporary anchorage devices to facilitate orthodontic movements. miniscrew loosening is a common problem, which usually occurs during the first two weeks of treatment. macrodesign can affect the stability of a miniscrew by changing its diameter, length, thread pitch, thread shape, tapering angle and so on. in this study, a 3-d finite element analysis wa...

Background: Thalassaemia is the single most common gene disorder in the world and represents major health burden. The most common oral and craniofacial manifestations are enlargement of maxilla, bossing of the skull and prominent malar eminences. The aim of the study was to assess the radiological changes of the oral and craniofacial region in β thalassaemic children with in the age group of 12...

Although many stifle injuries will not be evident radiographically, radiology remains a commonly used modality due to convenience and accessibility for assessment of the stifle joint. A technique for radiographic imaging of the stifle has been described. Small osseous lesions may not be evident on radiographs due to superimposition of bone. Although digital radiography systems have offered tech...

background: glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. in patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. death of the trabecular meshwork cells may be a result of apoptosis. objective: to investigate the aqueous humor levels of soluble fas (sfas) and fas-ligand (sfasl) in ...

In the normal eye, the main resistance to aqueous outflow is in the outermost region of the trabecular meshwork, which is adjacent to and forms the inner wall of Schlemm's canal. In primary open-angle glaucoma, there is increased resistance to outflow, and we assume that the abnormal additional resistance is in the same location. Examinations of pathological anatomy show scarring and sclerosis ...