OBJECTIVE To investigate the aetiology of multiple ecchymoses associated with eosinophilia. SETTING Professorial Paediatric Unit (PPU) at Lady Ridgeway Hospital (LRH) for children, Colombo. DESIGN Prospective study from July 1998 to April 2000. MATERIALS AND METHODS Patients admitted to the PPU with multiple ecchymoses associated with an absolute eosinophilia (> 1 x 10(9)/1) were investig...

background: toxocariasis is a common disease around the world. our objective was to determine toxocara seroprevalence in humans in the city of isparta, southwest turkey, in respect of some determinants such as age, socio-economic level, residence in city center or rural area etc. methods: five hundred and thirty four individual participants from isparta center and 85 from asagi gokdere village ...

background: toxocariasis is a prevalent zoonosis disease caused by the closely related nematode species toxocara canis and toxocara cati which parasitise canidae and felidae respectively. in paratenic hosts, larvae of these worms cause multiple organ damage. however, how these paratenic hosts response to these worms and whether any common biomarker can be applied for diagnosis are still unclear...

background: toxocariasis is the clinical terms applied to infection of human with ascarid nematodes in the order ascaridida, named toxocara canis and t. cati . because in recent years in iran many people desire to keep pets (cats and dogs), and lacking of seroepidemiological study of toxocariasis in mashhad, we decided to determine the seroprevalence of toxocariasis among people who own cats an...

With the aim of estimating the incidence of infection by Toxocara among residents in the outskirts of Campinas (State of São Paulo, Brazil) two serological surveys, using ELISA anti-Toxocara tests, were performed in January 1999 and January 2000, involving, respectively, 138 and 115 individuals, 75 of which examined in both occasions. Among this group 67 individuals did not show the presence of...

In human toxocariasis, there are few approaches using immunological markers for diagnosis and therapeutic assessment. An immunoblot (IB) assay using excretory-secretory Toxocara canis antigen was standardized for monitoring IgG, IgE and IgA antibodies in 27 children with toxocariasis (23 visceral, three mixed visceral and ocular, and one ocular form) for 22-116 months after chemotherapy. IB sen...

BACKGROUND Human toxocariasis, a helminthozoonosis, is due to the migration of Toxocara species larvae into human organisms. Humans, especially children become infected by ingesting of embryonated eggs from soil, dirty hands, and raw vegetables. Seroprevalence of this infection is high in developed countries, especially in rural areas. The aim of this study was to investigate the seroepidemiolo...

An enzyme-immunoassay was developed to measure the concentration of serum antibody specific for the secretary antigens released by migrating toxocaral larvae. This technique was evaluated by testing sera from healthy UK adults, and from patients with and without toxocariasis. In 922 healthy adults, 2-6% were found to have elevated specific antibody levels. Elevated values were observed twice as...

It is well known that eosinophilia is a key pathogenetic component of toxocariasis. The objective of the present study was to determine if there is an association between peritoneal and blood eosinophil influx, mast cell hyperplasia and leukotriene B(4) (LTB(4)) production after Toxocara canis infection. Oral inoculation of 56-day-old Wistar rats (N = 5-7 per group) with 1000 embryonated eggs c...