The asymmetric unit of the crystal of the title compound (common name rivaroxaban), C19H18ClN3O5, contains two rivaroxaban mol-ecules with different conformations; the C-C-N-C torsion angles between the oxazolidine and thio-phene rings are -171.1 (7) and -106.8 (9)° in the two independent mol-ecules. In the crystal, classical N-H⋯O hydrogen bonds and weak C-H⋯O hydrogen bonds link the mol-ecule...

The title compound, C(11)H(11)BrN(4)O(3), features an ethane fragment substituted with an almost planar (r.m.s. deviation = 0.019 Å) imidazo[4,5-b]pyridone ring system and an envelope-shaped oxazolidine unit on separate C atoms. The N-CH(2)-CH(2)-N torsion angle is 52.5 (4)°. In the crystal, pairs of mol-ecules are linked by N-H⋯O hydrogen bonds into centrosymmetric dimers.

The asymmetric unit of the title compound, [Sn(C(6)H(5))(2)(C(14)H(11)N(3)O(3))], contains two crystallographically independent mol-ecules that differ predominantly in the torsion of the phenyl rings. In both mol-ecules, the Sn(IV) ion is in a distored trigonal-bipyramidal geometry. The Sn-O distances are in the range 2.055 (2)-2.143 (2) Å.

The title compound, C10H8BrF3N2, crystallizes with two independent mol-ecules in the asymmetric unit, which can be considered as being related by a pseudo-inversion center, so their conformations are different; the corresponding N=C-N-C torsion angles are 54.6 (5) and -50.5 (5)°. In the crystal, mol-ecules related by translation in [001] inter-act through short inter-molecular Br⋯F contacts [3....

In the title compound, C(15)H(13)N(3)O(4), the mol-ecule exists in a trans configuration with respect to the methyl-idene unit. The dihedral angle between the two benzene rings is 6.8 (2)°. The C-N-NH-C torsion angle is 3.4 (3)°. The mol-ecule possesses an intra-molecular N-H⋯O hydrogen bond. In the crystal structure, adjacent mol-ecules are linked through inter-molecular C-H⋯O hydrogen bonds, ...

In the title compound, C(18)H(18)O(2), the methyl acrylate substituent adopts an extended E conformation with all torsion angles close to 180°. The mean plane of the acrylate unit and the phenyl ring are approximately orthogonal to each other, making a dihedral angle of 81.40 (6)°. The position of the carbonyl group with respect to the olefinic double bond is typically S-trans. The crystal pack...

The asymmetric unit of the title compound, C(14)H(13)Cl(2)NO(2)S, contains three independent moleules. The torsion angles of the C-SO2-NH-C segments in the three mol-ecules are 67.5 (2), 83.4 (2) and -77.5 (2)°. The two aromatic rings are tilted relative to each other by 68.8 (1), 64.1 (1) and 68.5 (1)°. The crystal structure features dimers linked by pairs of N-H⋯O hydrogen bonds.

Two independent mol-ecules comprise the asymmetric unit of the title compound, C(12)H(11)N(3)O(2). These differ in terms of the relative orientations of the benzene rings as seen in the respective dihedral angles formed between the pyridine and benzene rings [17.42 (16) and 34.64 (16)°]. Both mol-ecules are twisted about the amine-tolyl N-C bonds [respective torsion angles = 22.3 (5) and 35.9 (...

In the title compound, C(15)H(14)N(2)O(5), the central amide C-C(=O)-N-C unit forms dihedral angles of 28.17 (13) and 26.47 (13)° with the two benzene rings, whereas the two benzene rings are almost coplanar, making a dihedral angle of 4.52 (13)°. The two meth-oxy and the nitro substituents are almost coplanar with their attached benzene rings, with C-O-C-C torsion angles of -1.3 (4) and -4.6 (...

The title compound, C(10)H(12)O(2)S, crystallizes with four mol-ecules in the asymmetric unit. The main conformational difference between these mol-ecules is the orientation of the acetyl groups with respect to the ring. Whereas one acetyl group is only slightly twisted with respect to the thio-phene ring [C-C-C-O torsion angles = 165.7 (4), -164.6 (4), 164.3 (4) and -163.6 (4)°], the other ace...