To the Editor: Vibrio cholerae is a water-borne pathogen that causes a severe watery diarrhea disease known as cholera. On the basis of variable somatic O antigen composition, >200 serogroups of V. cholerae have been recognized. Classical and El Tor are 2 well-established biotypes within the V. cholerae O1 serogroup, and they can be distinguished by differences in their biochemical reactions or...

In response to nutrient deficiency, eukaryotic cells activate macroautophagy, a degradative process in which proteins, organelles and cytoplasm are engulfed within unique vesicles called autophagosomes. Fusion of these vesicles with the endolysosomal compartment leads to breakdown of the sequestered material into amino acids and other simple molecules, which can be used as nutrient sources duri...

The Tor network is designed to provide users with low-latency anonymous communication. Tor clients build circuits with publicly listed relays to anonymously reach their destinations. Low-latency anonymous communication is also an essential property required by censorship circumvention tools and thus Tor has been widely used as a censorship resistance tool. However, since the Tor relays are publ...

-Most algor i thms in 3D computer vision rely on the pinhole camera model because of its simplicity, whereas virtually all imaging devices int roduce certain amoun t of nonlinear distort ion, where the radial dis tor t ion is the most severe part. Common approach to radial dis tor t ion is by the means of polynomial approximat ion, which introduces distortion-specific pa ramete rs into the came...

Mammalian target-of-rapamycin (mTOR) triggers S6 kinase (S6K) activation to phosphorylate targets linked to translation in response to energy, nutrients, and hormones. Pathways of TOR activation in plants remain unknown. Here, we uncover the role of the phytohormone auxin in TOR signalling activation and reinitiation after upstream open reading frame (uORF) translation, which in plants is depen...

Traffic correlation attacks to de-anonymize Tor users are possible when an adversary is in a position to observe traffic entering and exiting the Tor network. Recent work has brought attention to the threat of these attacks by network-level adversaries (e.g., Autonomous Systems). We perform a historical analysis to understand how the threat from AS-level traffic correlation attacks has evolved ...

To date, there has yet to be a study that characterizes the usage of a real deployed anonymity service. We present observations and analysis obtained by participating in the Tor network. Our primary goals are to better understand Tor as it is deployed and through this understanding, propose improvements. In particular, we are interested in answering the following questions: (1) How is Tor being...

The target of rapamycin (TOR) is a highly conserved Ser/Thr kinase that plays a central role in the control of cellular growth. TOR has a characteristic multidomain structure. Only the kinase domain has catalytic function; the other domains are assumed to mediate interactions with TOR substrates and regulators. Except for the rapamycin-binding domain, there are no high-resolution structural dat...

BACKGROUND Only a small number of patients survive out-of-hospital-cardiac-arrest (OHCA). The duration of CPR varies considerably and transportation of patients under CPR is often unsuccessful. Termination-of-resuscitation (TOR)-criteria aim to preclude futile resuscitation efforts. Our goal was to find out to which extent existing TOR-criteria can be transferred to paediatric OHCA-patients wit...